Evidence map›Paper›PMID 33564416›Full record

ArticleClinical kidney journal2021

Effectiveness and safety of ferric carboxymaltose therapy in peritoneal dialysis patients: an observational study.

Jose Portolés-Pérez, Beatriz Durá-Gúrpide, José Luis Merino-Rivas, Leyre Martín-Rodriguez, Covadonga Hevia-Ojanguren, Victor Burguera-Vion, Claudia Yuste-Lozano, Luisa Sánchez-García, Jose Ramon Rodriguez-Palomares, Vicente Paraiso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Jose Portolés-PérezNephrology Department, University Hospital Puerta de Hierro, Madrid, Spain.ORCID 0000-0002-2114-1385
Beatriz Durá-GúrpideNephrology Department, University Hospital Puerta de Hierro, Madrid, Spain.
José Luis Merino-RivasNephrology Department, University Hospital del Henares, Coslada, Madrid, Spain.
Leyre Martín-RodriguezNephrology Department, University Hospital Puerta de Hierro, Madrid, Spain.
Covadonga Hevia-OjangurenNephrology Department, University Hospital Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain.
Victor Burguera-VionRedInRen ISCiii 016/009 Public Research Net, Madrid, Spain.
Claudia Yuste-LozanoRedInRen ISCiii 016/009 Public Research Net, Madrid, Spain.
Luisa Sánchez-GarcíaNephrology Department, University Hospital Rio Hortega, Valladolid, Spain.
Jose Ramon Rodriguez-PalomaresNephrology Department, University Hospital de Guadalajara, Guadalajara, Spain.
Vicente ParaisoNephrology Department, University Hospital del Henares, Coslada, Madrid, Spain.
GCDP Study Group
Hospital Universitario Puerta de Hierro Majadahonda · ESHospital Universitario del Henares · ESHospital Universitario de Guadalajara · ESHospital Universitario Infanta Sofía · ESHospital Universitario Ramón y Cajal · ESHospital Universitario Río Hortega · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy of intravenous (IV) ferric carboxymaltose (FCM) has been demonstrated in haemodialysis and non-dialysis studies, but evidence is lacking in patients undergoing peritoneal dialysis (PD).

methodsThis multicentre, retrospective study evaluated the effectiveness and safety of FCM in patients on PD over 12 months. We retrospectively reviewed the electronic medical records of PD patients who initiated FCM treatment between 2014 and 2017 across seven Spanish centres.

resultsNinety-one patients were included in the safety population (mean ± SD age 57.7 ± 15.0 years) and 70 in the efficacy population (mean age 50.9 ± 14.5 years). No hypersensitivity reaction, FCM discontinuation or dose adjustment due to a serious adverse event (SAE) was registered in the safety population. The most common non-SAEs reported were headache (four events), mild hypotension (three events) and hypertension (two events), among others. In the efficacy population (

conclusionIn this multicentre, retrospective, real-world study conducted in the PD population, FCM was effective, safe and easy to administer during routine clinical visits.

Indexed as

anaemiachronic kidney diseaseferric carboxymaltoseiron deficiencyperitoneal dialysis

Identifiers

PMID33564416
PMCPMC7857829
OpenAlexW2990791704

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.