Evidence map›Paper›PMID 33564332›Full record

ArticleBeilstein journal of organic chemistry2021

Total synthesis of decarboxyaltenusin.

Lucas Warmuth, Aaron Weiß, Marco Reinhardt, Anna Meschkov, Ute Schepers, Joachim Podlech

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Natural resorcylic lactones derived from alternariol.Beilstein journal of organic chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucas WarmuthInstitute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Fritz-Haber-Weg 6, Germany.ORCID https://orcid.org/0000-0002-2234-028X
Aaron WeißInstitute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Fritz-Haber-Weg 6, Germany.ORCID https://orcid.org/0000-0002-1638-2002
Marco ReinhardtInstitute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Fritz-Haber-Weg 6, Germany.ORCID https://orcid.org/0000-0002-6401-719X
Anna MeschkovInstitute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Hermann-von-Helmholtz-Platz 1, Germany.
Ute SchepersInstitute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Hermann-von-Helmholtz-Platz 1, Germany.ORCID https://orcid.org/0000-0002-2736-6200
Joachim PodlechInstitute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Fritz-Haber-Weg 6, Germany.ORCID https://orcid.org/0000-0001-7881-6905

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The total synthesis of decarboxyaltenusin (5'-methoxy-6-methyl-[1,1'-biphenyl]-3,3',4-triol), a toxin produced by various mold fungi, has been achieved in seven steps in a yield of 31% starting from 4-methylcatechol and 1-bromo-3,5-dimethoxybenzene, where the longest linear sequence consists of five steps. The key reaction was a palladium-catalyzed Suzuki coupling of an aromatic boronate with a brominated resorcin derivative.

Indexed as

biarylsboronatesmycotoxinspolyketidesSuzuki coupling

Identifiers

PMID33564332
PMCPMC7849237

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.