Evidence map›Paper›PMID 33564244›Full record

ArticleInfection and drug resistance2021

In vitro Combined Inhibitory Activities of β-Lactam Antibiotics and Clavulanic Acid Against

Mingjia Peng, Renru Han, Yan Guo, Yonggui Zheng, Feifei Yang, Xiaogang Xu, Fupin Hu

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mingjia PengInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-7588-3667
Renru HanInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yan GuoInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yonggui ZhengInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Feifei YangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Xiaogang XuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Fupin HuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe spread of KPC-producing Enterobacteriaceae has triggered a global public health concern, with KPC-2-positive strains being the most prevalent in China. We hereby studied the in vitro combined inhibitory activities of three kinds of β-lactam antibiotics and clavulanic acid at different concentrations against MATERIALS AND

methodsIn this study, 153 clinically isolated

resultsThe MICs of all three combinations gradually declined with increments in the proportion of clavulanic acid in the regimens, and the most significant decline in the MIC

conclusionThe highest combined inhibitory activity of β-lactam antibiotics/clavulanic acid at low concentration ratios against

Indexed as

clavulanic acidcombined inhibitory activityEnterobacteriaceaeKPCβ-lactam antibiotic

Identifiers

PMID33564244
PMCPMC7866911
OpenAlexW3128277217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.