ArticleThe ISME journal2021
The amphibian microbiome exhibits poor resilience following pathogen-induced disturbance.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 84 citations in OpenAlex.
- Differential Immune Responses Correlate With Chytridiomycosis Severity in Italian Crested Newts.Molecular ecology · 2026Article
- Bsal susceptibility depends on host origin but not on skin microbiota in captive Pleurodeles waltl.Animal microbiome · 2025Article
- Article
- Seasonality Has Greater Influence on Amphibian Cutaneous Mycobiome than Host Species.Journal of fungi (Basel, Switzerland) · 2025Article
- Natural recolonization of the amphibian skin bacterial community following disruption by antibiotics.Proceedings. Biological sciences · 2025Article
- Effects of snake fungal disease (ophidiomycosis) on the skin microbiome across two major experimental scales.Conservation biology : the journal of the Society for Conservation Biology · 2025Article
- Research Status and Prospect of Amphibian Symbiotic Microbiota.Animals : an open access journal from MDPI · 2025Review
- Microbial Community Metabolism of Coral Reef Exometabolomes Broadens the Chemodiversity of Labile Dissolved Organic Matter.Environmental microbiology · 2025Article
- Skin microbiomes of frogs vary among body regions, revealing differences that reflect known patterns of chytrid infection.Frontiers in microbiology · 2025Article
- The impact of microbiome diversity and composition on host health and susceptibility to disease across amphibian life stages.Frontiers in amphibian and reptile science · 2025Article
- Skin Bacterial and Fungal Microbiome Responses to Diet Supplementation and Rewilding in the Critically Endangered Southern Corroboree Frog.Molecular ecology · 2024Article
- Coral high molecular weight carbohydrates support opportunistic microbes in bacterioplankton from an algae-dominated reef.mSystems · 2024Article
- The role of family and environment in determining the skin bacterial communities of captive aquatic frogs, Xenopus laevis.FEMS microbiology ecology · 2024Article
- Article
- Nor climate nor human impact factors: Chytrid infection shapes the skin bacterial communities of an endemic amphibian in a biodiversity hotspot.Ecology and evolution · 2024Article
- Herptile gut microbiomes: a natural system to study multi-kingdom interactions between filamentous fungi and bacteria.mSphere · 2024Article
- Coral thermal stress and bleaching enrich and restructure reef microbial communities via altered organic matter exudation.Communications biology · 2024Article
- Family shapes microbiome differences in Oklahoma salamanders.Frontiers in microbiomes · 2024Article
- Gene functions of theMicrobial genomics · 2024Article
- Bacterial community analysis of the skin microbiota of cultured Chinese giant salamander infected withFrontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infectious pathogens can disrupt the microbiome in addition to directly affecting the host. Impacts of disease may be dependent on the ability of the microbiome to recover from such disturbance, yet remarkably little is known about microbiome recovery after disease, particularly in nonhuman animals. We assessed the resilience of the amphibian skin microbial community after disturbance by the pathogen, Batrachochytrium dendrobatidis (Bd). Skin microbial communities of laboratory-reared mountain yellow-legged frogs were tracked through three experimental phases: prior to Bd infection, after Bd infection (disturbance), and after clearing Bd infection (recovery period). Bd infection disturbed microbiome composition and altered the relative abundances of several dominant bacterial taxa. After Bd infection, frogs were treated with an antifungal drug that cleared Bd infection, but this did not lead to recovery of microbiome composition (measured as Unifrac distance) or relative abundances of dominant bacterial groups. These results indicate that Bd infection can lead to an alternate stable state in the microbiome of sensitive amphibians, or that microbiome recovery is extremely slow-in either case resilience is low. Furthermore, antifungal treatment and clearance of Bd infection had the additional effect of reducing microbial community variability, which we hypothesize results from similarity across frogs in the taxa that colonize community vacancies resulting from the removal of Bd. Our results indicate that the skin microbiota of mountain yellow-legged frogs has low resilience following Bd-induced disturbance and is further altered by the process of clearing Bd infection, which may have implications for the conservation of this endangered amphibian.
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