Evidence map›Paper›PMID 33564090›Full record

ArticleScientific reports2021

Machine learning prediction models for prognosis of critically ill patients after open-heart surgery.

Zhihua Zhong, Xin Yuan, Shizhen Liu, Yuer Yang, Fanna Liu

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Big Data in cardiac surgery: real world and perspectives.Journal of cardiothoracic surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhihua ZhongCollege of Information Science and Technology, Jinan University, Guangzhou, China.
Xin YuanCollege of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Shizhen LiuDepartment of Nephrology, The First Affiliated Hospital of Jinan University, 613 W.Huangpu Avenue, Guangzhou, 510632, China.
Yuer YangCollege of Cyber Security, Jinan University, Guangzhou, China.
Fanna LiuDepartment of Nephrology, The First Affiliated Hospital of Jinan University, 613 W.Huangpu Avenue, Guangzhou, 510632, China. tliufana@jnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to build up multiple machine learning models to predict 30-days mortality, and 3 complications including septic shock, thrombocytopenia, and liver dysfunction after open-heart surgery. Patients who underwent coronary artery bypass surgery, aortic valve replacement, or other heart-related surgeries between 2001 and 2012 were extracted from MIMIC-III databases. Extreme gradient boosting, random forest, artificial neural network, and logistic regression were employed to build models by utilizing fivefold cross-validation and grid search. Receiver operating characteristic curve, area under curve (AUC), decision curve analysis, test accuracy, F1 score, precision, and recall were applied to access the performance. Among 6844 patients enrolled in this study, 215 patients (3.1%) died within 30 days after surgery, part of patients appeared liver dysfunction (248; 3.6%), septic shock (32; 0.5%), and thrombocytopenia (202; 2.9%). XGBoost, selected to be our final model, achieved the best performance with highest AUC and F1 score. AUC and F1 score of XGBoost for 4 outcomes: 0.88 and 0.58 for 30-days mortality, 0.98 and 0.70 for septic shock, 0.88 and 0.55 for thrombocytopenia, 0.89 and 0.40 for liver dysfunction. We developed a promising model, presented as software, to realize monitoring for patients in ICU and to improve prognosis.

Indexed as

Databases, FactualHeart DiseasesHospital MortalityModels, BiologicalNeural Networks, ComputerAgedCardiac Surgical ProceduresCritical IllnessDisease-Free SurvivalFemaleHumansMachine LearningMaleMiddle AgedSurvival Rate

Identifiers

PMID33564090
PMCPMC7873187

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.