ArticleNature communications2021
Reward-related choices determine information timing and flow across macaque lateral prefrontal cortex.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 25 citations in OpenAlex.
- Attentional selection drives information convergence within macaque lateral prefrontal cortex.PNAS nexus · 2026Article
- Reversed functional gradient in primate prefrontal cortex: Posterior dominance and frontopolar task-related deactivation.Science advances · 2026Article
- Neuronal dynamics, timing, and flow of sensory and choice-related information in auditory-prefrontal circuitry.Nature communications · 2026Article
- Frontal Eye Field Leads a Distributed Oculomotor Circuit for Abstract Categorical Decisions.bioRxiv : the preprint server for biology · 2026Article
- Long-term Learning Induces Plastic Changes in Frontostriatal Circuits.bioRxiv : the preprint server for biology · 2026Article
- Interactions across hemispheres in prefrontal cortex reflect global cognitive processing.Nature communications · 2026Article
- Contribution of amygdala to dynamic model arbitration under uncertainty.Nature communications · 2025Article
- Neural basis of dysexecutive and visuospatial impairments in Parkinson's disease with MCI: a task-based fNIRS study.NPJ Parkinson's disease · 2025Article
- Home-Cage Training for Non-Human Primates: An Opportunity to Reduce Stress and Study Natural Behavior in Neurophysiology Experiments.Animals : an open access journal from MDPI · 2025Review
- A Functional Magnetic Resonance Imaging Investigation of Hot and Cool Executive Functions in Reward and Competition.Sensors (Basel, Switzerland) · 2025Article
- Ventral frontostriatal circuitry mediates the computation of reinforcement from symbolic gains and losses.Neuron · 2024Article
- Different Subregions of Monkey Lateral Prefrontal Cortex Respond to Abstract Sequences and Their Components.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Different subregions of monkey lateral prefrontal cortex respond to abstract sequences and their components.bioRxiv : the preprint server for biology · 2024Article
- Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates.Nature communications · 2024Article
- A revised perspective on the evolution of the lateral frontal cortex in primates.Science advances · 2023Article
- Review
- Hierarchical Reinforcement Learning, Sequential Behavior, and the Dorsal Frontostriatal System.Journal of cognitive neuroscience · 2022Review
- Article
- Prefrontal cortical plasticity during learning of cognitive tasks.Nature communications · 2022Article
- Differential coding of goals and actions in ventral and dorsal corticostriatal circuits during goal-directed behavior.Cell reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Prefrontal cortex is critical for cognition. Although much is known about the representation of cognitive variables in the prefrontal cortex, much less is known about the spatio-temporal neural dynamics that underlie cognitive operations. In the present study, we examined information timing and flow across the lateral prefrontal cortex (LPFC), while monkeys carried out a two-armed bandit reinforcement learning task in which they had to learn to select rewarding actions or rewarding objects. When we analyzed signals independently within subregions of the LPFC, we found a task-specific, caudo-rostral gradient in the strength and timing of signals related to chosen objects and chosen actions. In addition, when we characterized information flow among subregions, we found that information flow from action to object representations was stronger from the dorsal to ventral LPFC, and information flow from object to action representations was stronger from the ventral to dorsal LPFC. The object to action effects were more pronounced in object blocks, and also reflected learning specifically in these blocks. These results suggest anatomical segregation followed by the rapid integration of information within the LPFC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.