Evidence map›Paper›PMID 33563884›Full record

Observational studyJournal of atherosclerosis and thrombosis2021

Thrombotic Lesions are Associated with Poor Outcomes after Endovascular Treatment in Patients with Non-Acute Aortoiliac Total Occlusions.

Yoshito Kadoya, Kan Zen, Osamu Iida, Yoshito Yamamoto, Daizo Kawasaki, Yasutaka Yamauchi, Yoshiaki Shintani, Teruyasu Sugano, Hiroyoshi Yokoi, Satoaki Matoba and 1 more

Open access · diamondAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of atherosclerosis and thrombosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Yoshito KadoyaDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.
Kan ZenDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.
Osamu IidaCardiovascular Centre, Kansai Rosai Hospital.
Yoshito YamamotoDepartment of Cardiovascular Medicine, Iwaki Kyoritsu General Hospital.
Daizo KawasakiCardiovascular Division, Morinomiya Hospital.
Yasutaka YamauchiCardiovascular Centre, Takatsu General Hospital.
Yoshiaki ShintaniCardiovascular Centre, Ageo Central General Hospital.
Teruyasu SuganoDepartment of Cardiovascular Medicine, Yokohama City University Hospital.
Hiroyoshi YokoiCardiovascular Centre, Fukuoka Sanno Hospital.
Satoaki MatobaDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.
Masato NakamuraDivision of Cardiovascular Medicine, Toho University, Ohashi Medical Centre.
Kyoto Prefectural University of Medicine · JPHakodate Central General Hospital · JPIwaki Kyoritsu General Hospital · JPKansai Rosai Hospital · JPMorinomiya Hospital · JPSanno Medical Center · JPTakatsuki General Hospital · JPToho University · JPYokohama City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe post-endovascular treatment outcomes of thrombotic lesions remain unclear. This study aimed to investigate the effects of thrombotic lesions on post-endovascular treatment outcomes in patients with non-acute aortoiliac total occlusions.

methodsThis subanalysis of a multicenter prospective observational registry study included patients from 64 institutions in Japan between April 2014 and April 2016. A total of 346 patients (394 limbs; median age, 72 years), including 186 men, underwent endovascular treatment for non-acute aortoiliac total occlusions and were included. The patients were classified as having thrombotic or non-thrombotic lesions. The primary (1-year primary patency rate) and secondary (1-year overall survival rate) endpoints were evaluated.

resultsThrombotic lesions were identified in 18.5% (64/346) of the patients. The 1-year primary patency (85.9% versus 95.4%, log-rank p<.001) and overall survival (90.6% versus 97.9%, log-rank p=.003) rates were significantly lower in the thrombotic group than in the non-thrombotic group. Thrombotic lesions had significant effects on the post-endovascular treatment outcomes, with adjusted hazard ratios of 3.91 (95% confidence interval, 1.64-9.34, p=.002) for primary patency and 4.93 (95% confidence interval, 1.59-15.3, p=.006) for all-cause mortality.

conclusionsThrombotic lesions were associated with 1-year restenosis and all-cause mortality after endovascular treatment for non-acute aortoiliac total occlusions. Endovascular treatment strategies should be carefully planned for patients with thrombotic lesions.

Indexed as

Aorta, AbdominalArterial Occlusive DiseasesEndovascular ProceduresGraft Occlusion, VascularIliac ArteryThrombosisAgedExtremitiesFemaleHumansJapanMaleMortalityStentsTreatment OutcomeVascular PatencyAortoiliac vesselsEndovascular treatmentOutcome analysisPeripheral artery diseasesThrombotic lesion

Identifiers

PMID33563884
PMCPMC8629701
OpenAlexW3128947375

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.