Evidence map›Paper›PMID 33563871›Full record

ArticleThe Journal of reproduction and development2021

Lipid droplets are formed in 2-cell-like cells.

Asuka Furuta, Toshinobu Nakamura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of reproduction and development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. DUX: One Transcription Factor Controls 2-Cell-like Fate.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Asuka FurutaLaboratory for Epigenetic Regulation, Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga 526-0829, Japan.
Toshinobu NakamuraLaboratory for Epigenetic Regulation, Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga 526-0829, Japan.
Nagahama Institute of Bio-Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonic stem (ES) cells, derived from the inner cell mass of a blastocyst, are believed to pluripotent cells and give rise to embryonic, but not extraembryonic, tissues. In mice, totipotent 2-cell stage embryo-like (2-cell-like) cells, which are identified by reactivation of murine endogenous retrovirus with leucin transfer RNA primer (MuERV-L), arise at a very few frequencies in ES cell cultures. Here, we found that a lipid droplet forms during the transition from ES cells to 2-cell-like cells, and we propose that 2-cell-like cells utilize a unique energy storage and production pathway.

Indexed as

AnimalsBlastocystBoron CompoundsCell DifferentiationCell SeparationChromatinCytoplasmEmbryonic Stem CellsEndogenous RetrovirusesGlycolysisLipid DropletsLipidsMiceMicroscopy, ConfocalRNARNA, Transfer4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsChromatinLipidsRNARNA primersRNA, Transfer2-cell-like cellsLipid dropletMuERV-L positive cells

Identifiers

PMID33563871
PMCPMC8075727
OpenAlexW3128319863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.