Evidence map›Paper›PMID 33563829›Full record

ArticlemBio2021

An Indispensable Role for the MavE Effector of Legionella pneumophila in Lysosomal Evasion.

Bethany Vaughn, Kevin Voth, Christopher T Price, Snake Jones, Mateja Ozanic, Marina Santic, Miroslaw Cygler, Yousef Abu Kwaik

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Idiosyncratic Biogenesis of Intracellular Pathogens-Containing Vacuoles.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Bethany Vaughn *Department of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Kevin Voth *Department of Biochemistry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Christopher T PriceDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Snake JonesDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Mateja OzanicFaculty of Medicine, Department of Microbiology and Parasitology, University of Rijeka, Rijeka, Croatia.
Marina SanticFaculty of Medicine, Department of Microbiology and Parasitology, University of Rijeka, Rijeka, Croatia.
Miroslaw CyglerDepartment of Biochemistry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada miroslaw.cygler@usask.ca abukwaik@louisville.edu.ORCID 0000-0003-4579-1881
Yousef Abu KwaikDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA miroslaw.cygler@usask.ca abukwaik@louisville.edu.
University of Louisville · USUniversity of Rijeka · HRUniversity of Saskatchewan · CA

Funding

Innate immunity and inflammatory response of macrophages to Legionella infectionR01AI140195 · NIAID · UNIVERSITY OF LOUISVILLE · PI ABU KWAIK, YOUSEF A · 2018 to 2022
$1.9M
Molecular and Cellular Pathogenesis of LegionellaR01AI120244 · NIAID · UNIVERSITY OF LOUISVILLE · PI ABU KWAIK, YOUSEF A · 2015 to 2019
$1.9M
CIHR MOP 48370NIAID NIH HHS R01 AI120244NIAID NIH HHS R01 AI140195
6 · The paper itself

Abstract

Diversion of the

Indexed as

AnimalsBacterial ProteinsCells, CulturedCrystallizationHost-Pathogen InteractionsHumansLegionella pneumophilaLysosomesMacrophagesMiceProtein TransportVacuolesVirulenceBacterial ProteinsLegionnaires’lysosomal evasionMavENPxYtrafficking

Identifiers

PMID33563829
PMCPMC7885109
OpenAlexW3127615945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.