Evidence map›Paper›PMID 33563719›Full record

ArticleGenome research2021

Topologically associating domains and their role in the evolution of genome structure and function in

Yi Liao, Xinwen Zhang, Mahul Chakraborty, J J Emerson

Abstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Haplotype-Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Population genomics ofbioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi LiaoDepartment of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA.ORCID 0000-0002-7724-1799
Xinwen ZhangDepartment of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA.ORCID 0000-0003-2500-4756
Mahul ChakrabortyDepartment of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA.ORCID 0000-0003-2414-9187
J J EmersonDepartment of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA.

Funding

Structural variation population size and the evolution of genome complexityR01GM123303 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI EMERSON, JAMES JORDAN · 2017 to 2021
$1.5M
Evolutionary and functional consequences of structural genetic variation in DrosophilaK99GM129411 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHAKRABORTY, MAHUL · 2019 to 2021
$145k
NIGMS NIH HHS K99 GM129411NIGMS NIH HHS R01 GM123303
6 · The paper itself

Abstract

Topologically associating domains (TADs) were recently identified as fundamental units of three-dimensional eukaryotic genomic organization, although our knowledge of the influence of TADs on genome evolution remains preliminary. To study the molecular evolution of TADs in

Indexed as

Evolution, MolecularAnimalsChromatinDrosophilaDrosophila melanogasterFemaleGenome, InsectGenomicsMaleChromatin

Identifiers

PMID33563719
PMCPMC7919452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.