Evidence map›Paper›PMID 33563718›Full record

ArticleGenome research2021

Evolution of genome structure in the

Mahul Chakraborty, Ching-Ho Chang, Danielle E Khost, Jeffrey Vedanayagam, Jeffrey R Adrion, Yi Liao, Kristi L Montooth, Colin D Meiklejohn, Amanda M Larracuente, J J Emerson

Abstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Article
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  9. Article
  10. The histone gene family inmicroPublication biology · 2026
    Article
  11. Retention of a singlebioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Recent horizontal transfer of transposable elements inbioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahul Chakraborty *Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92697, USA.ORCID 0000-0003-2414-9187
Ching-Ho Chang *Department of Biology, University of Rochester, Rochester, New York 14627, USA.ORCID 0000-0001-9361-1190
Danielle E KhostDepartment of Biology, University of Rochester, Rochester, New York 14627, USA.
Jeffrey VedanayagamDepartment of Developmental Biology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.ORCID 0000-0002-5013-7860
Jeffrey R AdrionInstitute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA.ORCID 0000-0003-1021-6000
Yi LiaoDepartment of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92697, USA.ORCID 0000-0002-7724-1799
Kristi L MontoothSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska 68502, USA.ORCID 0000-0001-9456-6694
Colin D MeiklejohnSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska 68502, USA.ORCID 0000-0003-2708-8316
Amanda M LarracuenteDepartment of Biology, University of Rochester, Rochester, New York 14627, USA.ORCID 0000-0001-5944-5686
J J EmersonDepartment of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92697, USA.ORCID 0000-0001-9474-0891

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
The evolutionary and functional genomics of satellite DNAR35GM119515 · NIGMS · UNIVERSITY OF ROCHESTER · PI Amanda Marie Larracuente · 2016 to 2026
$4.0M
Structural variation population size and the evolution of genome complexityR01GM123303 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI EMERSON, JAMES JORDAN · 2017 to 2021
$1.5M
Investigating the special role of sex chromosomes in speciation: discovering the molecular identities, functions, and evolutionary histories of X-linked hybrid male sterility genes in DrosophilaR01GM123194 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI MEIKLEJOHN, COLIN D · 2017 to 2020
$1.3M
High-Throughput DNA SequencerS10OD021718 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2016 to 2016
$600k
PacBio RS Single Molecule, Real-Time (SMRT) DNA SequencerS10OD010794 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2012 to 2012
$600k
High Throughput DNA SequencerS10RR025496 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2009 to 2009
$500k
Evolutionary and functional consequences of structural genetic variation in DrosophilaK99GM129411 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHAKRABORTY, MAHUL · 2019 to 2021
$145k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA062203NCRR NIH HHS S10 RR025496NIGMS NIH HHS K99 GM129411NIGMS NIH HHS R01 GM123194NIGMS NIH HHS R01 GM123303NIGMS NIH HHS R35 GM119515NIH HHS S10 OD010794NIH HHS S10 OD021718
6 · The paper itself

Abstract

The rapid evolution of repetitive DNA sequences, including satellite DNA, tandem duplications, and transposable elements, underlies phenotypic evolution and contributes to hybrid incompatibilities between species. However, repetitive genomic regions are fragmented and misassembled in most contemporary genome assemblies. We generated highly contiguous de novo reference genomes for the

Indexed as

Evolution, MolecularAnimalsDNA Copy Number VariationsDNA, SatelliteDNA Transposable ElementsDrosophila melanogasterDrosophila simulansFemaleGenome, InsectMaleDNA, SatelliteDNA Transposable Elements

Identifiers

PMID33563718
PMCPMC7919458

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.