ArticleBMJ case reports2021
Graves' disease presenting with hypomania and paranoia to the acute psychiatry service.
Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Psychotic depression associated with Graves' disease: A case report on treatment prioritization.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Article
- The association between thyroid hormone levels and psychiatric symptoms in patients with mania or depression.Endocrine journal · 2026Article
- Is There a Link Between TSH Levels and Schizophrenia? A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Case report: Diagnosis of impaired consciousness in a cancer patient using immune checkpoint inhibitors.Frontiers in immunology · 2025Article
- Non-linear relationship between TSH and psychotic symptoms on first episode and drug naïve major depressive disorder patients: a large sample sized cross-sectional study in China.BMC psychiatry · 2024Article
- Postpartum Psychosis as a Consequence of Thyroiditis Versus Relapse: A Diagnostic Dilemma.Cureus · 2024Article
- Article
- Case report: Impact of hyperthyroidism on psychotic symptoms in schizophrenia comorbid with Graves' disease.Frontiers in psychiatry · 2023Article
- Neuropsychiatric Manifestations of Thyroid Diseases.Cureus · 2023Review
- Article
- Management of Psychosis Associated with Graves' Disease: A Rare Case Report.Case reports in psychiatry · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This manuscript describes the case of a young woman, with no prior psychiatric history, who developed hypomania and paranoia as the principal presenting features of Graves' disease. After starting treatment with carbimazole and propranolol, symptoms resolved without the use of antipsychotic drugs. Close liaison between psychiatry and endocrinology services was essential. This demonstrates that treating underlying thyrotoxicosis in patients presenting with psychiatric symptoms may lead to recovery without the use of antipsychotic medication. While agitation, irritability and mood lability are well-recognised thyrotoxic symptoms, psychosis is a rare presenting feature of Graves' disease. All patients with agitation, delirium or psychiatric symptoms should have thyroid function checked as part of initial tests screening for organic disease. In new or relapsing psychiatric conditions, it is important to ask patients, their carers or relatives about symptoms of hypothyroidism or thyrotoxicosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.