Evidence map›Paper›PMID 33563312›Full record

ArticleJournal of occupational medicine and toxicology (London, England)2021

Oxidative stress induction in woodworkers occupationally exposed to wood dust and formaldehyde.

Federica Ghelli, Valeria Bellisario, Giulia Squillacioti, Elena Grignani, Giacomo Garzaro, Martina Buglisi, Enrico Bergamaschi, Roberto Bono

Open access · goldAbstract read
In one paragraph

Article in Journal of occupational medicine and toxicology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Federica GhelliDepartment of Public Health and Pediatrics, University of Turin, via Santena 5 bis, 10126, Turin, Italy.
Valeria BellisarioDepartment of Public Health and Pediatrics, University of Turin, via Santena 5 bis, 10126, Turin, Italy.
Giulia SquillaciotiDepartment of Public Health and Pediatrics, University of Turin, via Santena 5 bis, 10126, Turin, Italy.
Elena GrignaniMaugeri Scientific Clinical Institutes, Via Salvatore Maugeri, 10, 27100, Pavia, Italy.
Giacomo GarzaroDepartment of Public Health and Pediatrics, University of Turin, via Zuretti 29, 10126, Turin, Italy.
Martina BuglisiDepartment of Public Health and Pediatrics, University of Turin, via Santena 5 bis, 10126, Turin, Italy.
Enrico BergamaschiDepartment of Public Health and Pediatrics, University of Turin, via Zuretti 29, 10126, Turin, Italy.
Roberto BonoDepartment of Public Health and Pediatrics, University of Turin, via Santena 5 bis, 10126, Turin, Italy. roberto.bono@unito.it.ORCID http://orcid.org/0000-0002-2471-6594
University of Turin · ITDepartment of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany workers are exposed to wood dust (WD) and formaldehyde (FA), whose carcinogenic activity is supposed to be oxidative stress-mediated. This study aims to assess to what extent the occupational exposure to WD and FA, albeit within regulatory limits, could result in OS induction in a woodworkers' population.

methodsThe sample population consisted of 127 woodworkers from 4 factories and 111 unexposed controls. Individual exposure was assessed by personal air-samplers. Each participant enrolled in the study filled out a questionnaire and provided a urinary sample to quantify OS biomarkers, namely 15-F

resultsWoodworkers were exposed to significantly higher amounts of WD and FA as compared to controls (p < 0.001). Among OS biomarkers, 15-F

conclusionsThe study confirms that WD and FA may induce OS in woodworkers, and highlights that even the compliance with occupational exposure limits can result in measurable biological outcomes.

Indexed as

BiomonitoringEpidemiologyFormaldehydeOccupational hygieneWood dust

Identifiers

PMID33563312
PMCPMC7871551
OpenAlexW3128423153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.