Evidence map›Paper›PMID 33563259›Full record

ArticleBMC women's health2021

Association between body mass index and fragility fracture in postmenopausal women: a cross-sectional study using Korean National Health and Nutrition Examination Survey 2008-2009 (KNHANES IV).

Jihan Kim, Sami Lee, Sung Soo Kim, Jong-Pyo Lee, Jong Sung Kim, Jin Gyu Jung, Seok Jun Yoon, Kyu Pil Kim, Chan-Keol Park, Yong-Hwan Kim

Abstract read
In one paragraph

Article in BMC women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study : Bone fracture and 30-year BMI trajectories.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Prevalence and Predictors of Osteoporosis and Osteopenia in Postmenopausal Women of Punjab, India.International journal of environmental research and public health · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jihan KimDepartment of Family Medicine, Sejong Trinium Woman's Hospital, Sejong, Korea.
Sami LeeDepartment of Family Medicine, Research Institute for Medical Science, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-Gu, Daejeon, 35015, Korea. smlee@cnuh.co.kr.ORCID 0000-0003-3653-7734
Sung Soo KimDepartment of Family Medicine, Research Institute for Medical Science, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-Gu, Daejeon, 35015, Korea.
Jong-Pyo LeeDepartment of Obstetrics and Gynecology, Sejong Trinium Woman's Hospital, Sejong, Korea.
Jong Sung KimDepartment of Family Medicine, Research Institute for Medical Science, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-Gu, Daejeon, 35015, Korea.
Jin Gyu JungDepartment of Family Medicine, Research Institute for Medical Science, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-Gu, Daejeon, 35015, Korea.
Seok Jun YoonDepartment of Family Medicine, Research Institute for Medical Science, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-Gu, Daejeon, 35015, Korea.
Kyu Pil KimDepartment of Family Medicine, Chungnam National University Sejong Hospital, Sejong, Korea.
Chan-Keol ParkDivision of Rheumatology, Department of Internal Medicine, Chungnam National University Sejong Hospital, Sejong, Korea.
Yong-Hwan KimDepartment of Orthopedic Surgery, Chungnam National University Hospital, Daejeon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study examined the relationship between body mass index (BMI) and the risk for fragility fractures in postmenopausal Korean women.

methodsAmong subjects who participated in the 4th Korea National Health and Nutrition Examination Survey (2008-2009), 2114 women ≥ 40 years of age were included. BMI was based on standards set by the Korean Society for the Study of Obesity, as follows: < 18.5 kg/m

resultsThe mean (± SD) rate of fragility fracture was significantly different among the three groups: 5.9 ± 2.9% (underweight), 1.1 ± 0.3% (normal weight), and 3.0 ± 0.7% (obese) (p = 0.001). After correcting for age, family history, and treatment history of osteoporosis and rheumatoid arthritis, smoking and drinking status, and level of exercise, multivariable regression analysis revealed that the odds ratio for fragility fracture in the underweight group was 5.48 [95% confidence interval (CI) 1.80-16.73] and 3.33 (95% CI 1.61-6.87) in the obese group. After subdividing fragility fractures into vertebral and non-vertebral, the odds ratio for vertebral fracture in the underweight group was 5.49 (95% CI 1.31-23.09) times higher than that in the normal weight group; in the obese group, the non-vertebral fracture odds ratio was 3.87 (95% CI 1.45-10.33) times higher. Analysis of non-vertebral fractures in the obese group revealed an odds ratio for fracture 22.05 (95% CI 1.33-365.31) times higher for hip fracture and 3.85 (95% CI 1.35-10.93) times higher for wrist fracture.

conclusionsObesity and underweight increased the risk for fragility fractures in postmenopausal Korean women.

Indexed as

Osteoporosis, PostmenopausalPostmenopauseBody Mass IndexBone DensityCross-Sectional StudiesFemaleHumansNutrition SurveysRepublic of KoreaRisk FactorsBody mass indexObesityOsteoporosisOsteoporotic fracturesPostmenopausal

Identifiers

PMID33563259
PMCPMC7871625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.