ArticleBMC infectious diseases2021
Detection of Nipah virus in Pteropus medius in 2019 outbreak from Ernakulam district, Kerala, India.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Risk of Nipah Virus Seroprevalence in Healthcare Workers: A Systematic Review with Meta-Analysis.Viruses · 2025Pooled it
- Post-mortem surveillance: an innovative strategy to detect and prevent spread of Nipah virus infection in humans.Emerging microbes & infections · 2026Article
- The Nipah virus threat in India: Epidemiological trends, risk drivers, and lessons for pandemic preparedness.PLoS pathogens · 2026Review
- Nipah Virus Encephalitis: Pathogenetic Aspects and Current Therapeutic Strategies.Pathogens (Basel, Switzerland) · 2026Review
- Strengthening preparedness and response to emerging henipavirus diversity.Frontiers in cellular and infection microbiology · 2026Review
- Effect of temperature and time on RNA detection by RT-qPCR in rodent tissue and blood samples stored in MagMAX™ Lysis/Binding Solution Concentrate: Considerations for RNA detection in specimens stored under suboptimal conditions.Journal of virological methods · 2025Article
- Review
- Article
- Nipah virus: pathogenesis, genome, diagnosis, and treatment.Applied microbiology and biotechnology · 2025Review
- Nipah virus infection in humans in Kerala, India: Hypothesis of air-borne transmission.The Indian journal of medical research · 2025Article
- Strengthening Public Health Systems to Combat the Rising Threat of Nipah Virus: A Call for Global Preparedness and Response.Advances in experimental medicine and biology · 2025Review
- Identification of CD8+ Immunogenic Peptides for Vaccine Design against Nipah Virus in Humans.Iranian journal of public health · 2024Article
- Nipah virus: epidemiology, pathogenesis, treatment, and prevention.Frontiers of medicine · 2024Review
- Nipah Virus Outbreaks in Kerala: An Impending Doom?Health science reports · 2024Article
- Nipah virus survey inFrontiers in microbiology · 2024Article
- Recurrent Nipah outbreaks in Kerala: implications for health policy and preparedness.Frontiers in public health · 2024Article
- Surveillance of Nipah virus inFrontiers in microbiology · 2024Article
- Pandemic potential of the Nipah virus and public health strategies adopted during outbreaks: Lessons from Kerala, India.PLOS global public health · 2024Review
- Review
- Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate).Virulence · 2023Article
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Authors and funding
16 authors at 2 institutions in 1 country.
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Abstract
backgroundIn June 2019, Nipah virus (NiV) infection was detected in a 21-year-old male (index case) of Ernakulum, Kerala, India. This study was undertaken to determine if NiV was in circulation in Pteropus species (spp) in those areas where the index case had visit history in 1 month.
methodsSpecialized techniques were used to trap the Pteropus medius bats (random sampling) in the vicinity of the index case area. Throat and rectal swabs samples of 141 bats along with visceral organs of 92 bats were collected to detect the presence of NiV by real-time reverse transcriptase-polymerase chain reaction (qRTPCR). Serum samples of 52 bats were tested for anti-NiV Immunoglobulin (Ig) G antibodies by Enzyme-Linked Immunosorbent Assay (ELISA). The complete genome of NiV was sequenced by next-generation sequencing (NGS) from the tissues and swab samples of bats.
resultsOne rectal swab sample and three bats visceral organs were found positive for the NiV. Interestingly, 20.68% (12/58) of Pteropus were positive for anti-NiV IgG antibodies. NiV sequences of 18,172; 17,200 and 15,100 nucleotide bps could be retrieved from three Pteropus bats.
conclusionA distinct cluster of NiV sequences, with significant net-evolutionary nucleotide divergence, was obtained, suggesting the circulation of new genotype (I-India) in South India. NiV Positivity in Pteropus spp. of bats revealed that NiV is circulating in many districts of Kerala state, and active surveillance of NiV should be immediately set up to know the hotspot area for NiV infection.
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