Evidence map›Paper›PMID 33563009›Full record

ReviewStroke2021

The Utility of Domain-Specific End Points in Acute Stroke Trials.

Steven C Cramer, Steven L Wolf, Jeffrey L Saver, Karen C Johnston, J Mocco, Maarten G Lansberg, Sean I Savitz, David S Liebeskind, Wade Smith, Max Wintermark and 5 more

Abstract readReview
In one paragraph

Review in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Steven C CramerDepartment of Neurology, David Geffen School of Medicine at the University of California, Los Angeles (S.C.C., J.L.S., D.S.L.).
Steven L WolfDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA (S.L.W.).
Jeffrey L SaverDepartment of Neurology, David Geffen School of Medicine at the University of California, Los Angeles (S.C.C., J.L.S., D.S.L.).
Karen C JohnstonDepartment of Neurology, University of Virginia, Charlottesville (K.C.J.).
J MoccoDepartment of Neurosurgery, Mt. Sinai, New York (J.M.).
Maarten G LansbergDepartment of Neurology, Stanford University, CA (M.G.L.).
Sean I SavitzInstitute for Stroke and Cerebrovascular Disease, University of Texas Health Science Center, Houston (S.I.S.).
David S LiebeskindDepartment of Neurology, David Geffen School of Medicine at the University of California, Los Angeles (S.C.C., J.L.S., D.S.L.).
Wade SmithDepartment Neurology, University of California, San Francisco (W.S.).
Max WintermarkDepartment of Radiology, Stanford University, CA (M.W.).
Jordan J ElmDepartment of Public Health Sciences, Medical University of South Carolina, Charleston (J.J.E.).
Pooja KhatriDepartment of Neurology, University of Cincinnati (P.K.).
Joseph P BroderickDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati Gardner Neuroscience Institute, University of Cincinnati Academic Health Center, OH (J.P.B.).
Scott JanisDivision of Clinical Research, The National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (S.J.).
NIH StrokeNet Recovery and Rehabilitation Group and the Acute Stroke Group*

Funding

NSTN National Clinical Coordinating CenterU01NS086872 · NINDS · UNIVERSITY OF CINCINNATI · PI Joseph Paul Broderick, Pooja Khatri · 2013 to 2026
$32.3M
Workshop to Identify Collaborative Project(s) for the NIH StrokeNet and the Japan NEtwork for Clinical Stroke Trials (NECST)U01NS087748 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Catherine R. Dillon, Jordan J. Elm · 2014 to 2026
$14.1M
NINDS NIH HHS U01 NS086872
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endpoint DeterminationHumansResearch DesignStrokeTreatment Outcomebraininfarctionneuronsoutcome assessmentreperfusion

Identifiers

PMID33563009
PMCPMC7902441

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.