ArticleViruses2021
High Diversity of Human Non-Polio Enterovirus Serotypes Identified in Contaminated Water in Nigeria.
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 28 citations in OpenAlex.
- Serotypes distribution characteristic of enterovirus in sewage in Hangzhou, Zhejiang Province from January 2023 to December 2024.Virology journal · 2026Article
- Environmental surveillance of pathogens in Africa.Applied and environmental microbiology · 2026Review
- Higher stability of novel live-attenuated oral poliovirus type 2 (nOPV2) despite the emergence of a neurovirulent double recombinant strain in Uganda.Nature microbiology · 2026Article
- Molecular characterization of enteroviruses in patients with acute respiratory infection and influenza-like illness in the Central African Republic revealed mainly polioviruses and other enteric enterovirus types.Access microbiology · 2026Article
- Metagenomic analysis and genomic characterization of enterovirus A76 and Norovirus GI.6[P11] co-infection in a patient with acute gastroenteritis in Thailand.Scientific reports · 2025Article
- Global Prevalence of Non-Polio Enteroviruses Pre- and Post COVID-19 Pandemic.Microorganisms · 2025Review
- Wastewater monitoring allows the detection of uncommon and highly pathogenic enterovirus types.Applied and environmental microbiology · 2025Article
- Evaluating enterovirus diversity among symptomatic patients in Hungary during and after easing the COVID-19 lockdown.Virology journal · 2025Article
- A 3-Year Environmental Surveillance Reveals Multiple Enteroviruses Including Types A76, A89, A90 and C113 in Eastern China.Food and environmental virology · 2025Article
- Enteroviruses in Water: Epidemiology, Detection and Inactivation.Environmental microbiology · 2025Review
- Direct amplification and sequencing of enterovirus genomes from clinical and wastewater samples reveals uncommon virus types in Cameroon.Archives of virology · 2025Article
- The genetic and proliferation characterization analysis of novel coxsackievirus A12 in Beijing, China.Frontiers in microbiology · 2025Article
- Characterization of enteroviruses circulating among farm animals and children in Central African Republic.Emerging microbes & infections · 2024Article
- First whole genome sequencing and analysis of human parechovirus type 3 causing a healthcare-associated outbreak among neonates in Hungary.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Estimating prevalence of Enterovirus D111 in human and non-human primate populations using cross-sectional serology.The Journal of general virology · 2023Article
- Nearly Complete Genome Sequence of Enterovirus Type A119 from Sewage in France in 2015.Microbiology resource announcements · 2023Article
- Molecular characteristics of a coxsackievirus A12 strain in Zhejiang of China, 2019.Virology journal · 2022Article
- Genomic analysis of a recombinant coxsackievirus A19 identified in Xinxiang, China, in 2019.Archives of virology · 2022Article
- Detection of Enterovirus D68 in Wastewater Samples from the UK between July and November 2021.Viruses · 2022Article
- Genetic characterization and molecular epidemiology of Coxsackievirus A12 from mainland China during 2010-2019.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Human enteroviruses (EVs) are highly prevalent in sewage and have been associated with human diseases with complications leading to severe neurological syndromes. We have used a recently developed molecular method to investigate the presence of EVs in eight samples collected in 2017-2018 from water streams contaminated by drainage channels in three different locations in Nigeria. A total of 93 human EV strains belonging to 45 different serotypes were identified, far exceeding the number of strains and serotypes found in similar samples in previous studies. Next generation sequencing analysis retrieved whole-capsid genomic nucleotide sequences of EV strains belonging to all four A, B, C, and D species. Our results further demonstrate the value of environmental surveillance for the detection of EV transmission of both serotypes commonly associated with clinical syndromes, such as EV-A71, and those that appear to circulate silently but could eventually cause outbreaks and disease. Several uncommon serotypes, rarely reported elsewhere, were detected such as EV-A119, EV-B87, EV-C116, and EV-D111. Ten EV serotypes were detected in Nigeria for the first time and two of them, CV-A12 and EV-B86, firstly described in Africa. This method can be expanded to generate whole-genome EV sequences as we show here for one EV-D111 strain. Our data revealed phylogenetic relationships of Nigerian sewage strains with EV strains reported elsewhere, mostly from African origin, and provided new insights into the whole-genome structure of emerging serotype EV-D111 and recombination events among EV-D serotypes.
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