Evidence map›Paper›PMID 33562680›Full record

ArticleMolecules (Basel, Switzerland)2021

Exploring the Distinct Binding and Activation Mechanisms for Different CagA Oncoproteins and SHP2 by Molecular Dynamics Simulations.

Quan Wang, Wen-Cheng Zhao, Xue-Qi Fu, Qing-Chuan Zheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A review of signal pathway induced by virulent protein CagA ofFrontiers in cellular and infection microbiology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Quan WangEdmond H. Fischer Signal Transduction Laboratory, College of Life Sciences, Jilin University, Changchun 130023, China.
Wen-Cheng ZhaoEdmond H. Fischer Signal Transduction Laboratory, College of Life Sciences, Jilin University, Changchun 130023, China.
Xue-Qi FuEdmond H. Fischer Signal Transduction Laboratory, College of Life Sciences, Jilin University, Changchun 130023, China.
Qing-Chuan ZhengLaboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, International Joint Research Laboratory of Nano-Micro Architecture Chemistry, Jilin University, Changchun 130023, China.
Jilin University · CN

Funding

National Natural Science Foundation of China No.31670795
6 · The paper itself

Abstract

CagA is a major virulence factor of

Indexed as

Molecular Dynamics SimulationAllosteric RegulationAntigens, BacterialBacterial ProteinsEnzyme ActivationHydrogen BondingMolecular Docking SimulationProtein BindingProtein ConformationProtein Tyrosine Phosphatase, Non-Receptor Type 11ThermodynamicsAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriProtein Tyrosine Phosphatase, Non-Receptor Type 11allostericEPIYAH. pyloriMD simulationsSHP2

Identifiers

PMID33562680
PMCPMC7916045
OpenAlexW3127862524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.