Evidence map›Paper›PMID 33562558›Full record

ArticleJournal of clinical medicine2021

Dynamic Susceptibility Perfusion Imaging for Differentiating Progressive Disease from Pseudoprogression in Diffuse Glioma Molecular Subtypes.

Vivien Richter, Uwe Klose, Benjamin Bender, Katharina Rabehl, Marco Skardelly, Jens Schittenhelm, Ghazaleh Tabatabai, Johann-Martin Hempel, Ulrike Ernemann, Cornelia Brendle

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Vivien RichterDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.ORCID 0000-0002-4723-1055
Uwe KloseDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.ORCID 0000-0001-5236-3450
Benjamin BenderDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.ORCID 0000-0002-3205-4631
Katharina RabehlDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.
Marco SkardellyDepartment of Neurosurgery, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.
Jens SchittenhelmDepartment of Neuropathology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.ORCID 0000-0002-9168-6209
Ghazaleh TabatabaiInterdisciplinary Section of Neurooncology, Department of Neurology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.
Johann-Martin HempelDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.
Ulrike ErnemannDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.
Cornelia BrendleDepartment of Neuroradiology, Universitätsklinikum Tübingen, 72070 Tübingen, Germany.ORCID 0000-0002-2276-4867
Universitätsklinikum Tübingen · DE

Funding

Universitätsklinikum Tübingen TÜFF 2523-0-0
6 · The paper itself

Abstract

RATIONALE AND

objectivesAdvanced adjuvant therapy of diffuse gliomas can result in equivocal findings in follow-up imaging. We aimed to assess the additional value of dynamic susceptibility perfusion imaging in the differentiation of progressive disease (PD) from pseudoprogression (PsP) in different molecular glioma subtypes. MATERIALS AND

methods89 patients with treated diffuse glioma with different molecular subtypes (IDH wild type (Astro-IDH

resultsThe PD rate was 69% in the whole cohort, 86% in Astro-IDH

conclusionUtilizing combined information about the molecular tumor type, the presence or absence of CE lesions and rCBV parameters increases PD prediction accuracy in diffuse glioma.

Indexed as

diffuse gliomaDSC-MRIDTMdynamic susceptibility perfusion imagingprogressive diseasepseudoprogression

Identifiers

PMID33562558
PMCPMC7915936
OpenAlexW3127232488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.