ReviewCells2021
Malignant Melanoma of the Gastrointestinal Tract: Symptoms, Diagnosis, and Current Treatment Options.
Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 89 citations in OpenAlex.
- Recurrent Jejunal Melanoma Presenting as Obscure Gastrointestinal Bleeding: A Diagnostic Challenge.ACG case reports journal · 2026Article
- Emergency surgery for intestinal obstruction caused by gastrointestinal metastasis of malignant melanoma: a case report.Journal of surgical case reports · 2026Article
- Article
- Primary melanoma of the gastrointestinal tract.World journal of gastroenterology · 2026Review
- Ileal malignant melanoma presenting with severe iron-deficiency anemia and active small-bowel bleeding: primary intestinal melanoma versus metastasis - a case report and narrative review.Frontiers in oncology · 2026Article
- Acute Bleeding From Jejunal Malignant Melanoma With an Unusual Similar Lesion in the Right Parotid Gland.Case reports in surgery · 2026Article
- Primary Jejunal Melanoma Presenting as Widespread Metastases: Clinicopathological and Embryological Perspectives-A Case Report.Case reports in surgery · 2026Article
- Pancreatic metastasis from anorectal malignant melanoma.Clinical journal of gastroenterology · 2025Article
- Machine learning prediction of overall survival in patients with primary gastrointestinal melanoma.Translational cancer research · 2025Article
- Article
- From the Skin to Small Bowel: Metastatic Melanoma as a Hidden Source of Gastrointestinal Bleeding.Cureus · 2025Article
- Tumor-infiltrating lymphocytes in melanoma: diagnostic and prognostic implications from biopsy to circulation.The journal of liquid biopsy · 2025Review
- Malignant melanoma of the conjunctiva metastatic to the parotid gland: a case report.Journal of medical case reports · 2025Article
- Article
- Tumoral Melanosis of the Colon: A Rare Manifestation of Regressed Melanoma.ACG case reports journal · 2025Article
- Potential metastatic mechanisms and clinical aspects in patients with non-gastrointestinal tumor metastasis to the upper gastrointestinal tract.Journal of gastrointestinal oncology · 2025Article
- Article
- Article
- Intramural Intestinal Metastasis of Malignant Melanoma as a Rare Cause of Ileoileal Intussusception: A Case Report and Review of the Literature.Case reports in surgery · 2025Article
- Cross-sectional imaging of mimics of inflammatory bowel disease: not everything is Crohn's disease or ulcerative colitis.Abdominal radiology (New York) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant melanoma (MM) has become the fifth most frequent cancer in the UK. It is the most common carcinoma to metastasize to the gastrointestinal (GI) tract. MM particularly has an affinity to spread to the small bowel, which is followed by the involvement of the stomach and large intestine. Excellent endoscopic options including video capsule endoscopy and enteroscopy are available for a precise diagnosis of GI involvement by a metastatic MM. The complete surgical resection of GI metastatic MM in carefully selected patients not only provides symptom control, but has also been associated with an increase in overall survival. The approval of BRAF-targeted therapies and immune checkpoint inhibitors has transformed therapeutic approaches for patients with metastatic MM over the past decade. Currently, the overall survival of patients with advanced metastatic MM who have been treated with a combination of immunotherapeutic agents reaches 52% at five years. The role of surgery for patients with the metastatic involvement of the GI tract with MM is evolving in the era of effective systemic treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.