Evidence map›Paper›PMID 33562451›Full record

ArticleInfectious disease reports2021

Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam.

Phuong M Nguyen, Anh N Thach, Xuan D Pham, Anh N Lam, Thao N P Nguyen, Chu X Duong, Lam V Nguyen, Thao H Nguyen, Suol T Pham, Katja Taxis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Phuong M NguyenDepartment of Pediatrics, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Anh N ThachSoc Trang Center for Disease Control, Soc Trang 96000, Vietnam.
Xuan D PhamDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan 320317, Taiwan.
Anh N LamDepartment of Epidemiology, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Thao N P NguyenDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Chu X DuongDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Lam V NguyenDepartment of Anatomy, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Thao H NguyenDepartment of Clinical Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh 710000, Vietnam.
Suol T PhamDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.
Katja TaxisGroningen Research Institute of Pharmacy, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0001-8539-2004
Thang NguyenDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho 900000, Vietnam.ORCID 0000-0001-7799-4523
Can Tho University · VNNational Central University · TWUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam.

methodsA cross-sectional study was conducted in a hospital in southern Vietnam from June to December 2019 on patients who began antiretroviral therapy (ART) for at least 6 months. Using a designed questionnaire, patients were considered adherent if they took correct medicines with right doses, on time and properly with food and beverage and had follow-up visits as scheduled. Multivariable logistic regression was used to identify determinants of adherence. KEY

findingsA total of 350 patients (from 861 medical records) were eligible for the study. The majority of patients were male (62.9%), and the dominant age group (≥35 years old) accounted for 53.7% of patients. Sexual intercourse was the primary route of transmission of HIV (95.1%). The proportions of participants who took the correct medicine and at a proper dose were 98.3% and 86.3%, respectively. In total, 94.9% of participants took medicine appropriately in combination with food and beverage, and 75.7% of participants were strictly adherent to ART. The factors marital status (odds ratio (OR) = 2.54; 95%CI = 1.51-4.28), being away from home (OR = 1.7; 95%CI = 1.03-2.78), substance abuse (OR = 2.7; 95%CI = 1.44-5.05), general knowledge about ART (OR = 2.75; 95%CI = 1.67-4.53), stopping medication after improvement (OR = 4.16; 95%CI = 2.29-7.56) and self-assessment of therapy adherence (OR = 9.83; 95%CI = 5.44-17.77) were significantly associated with patients' adherence.

conclusionsThree-quarters of patients were adherent to ART. Researchers should consider these determinants of adherence in developing interventions in further studies.

Indexed as

acquired immune deficiency syndrome (AIDS)antiretroviral therapy (ART)human immunodeficiency virus (HIV)medication adherenceVietnam

Identifiers

PMID33562451
PMCPMC7931092
OpenAlexW3128268241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.