ArticleNutrients2021
Association of Serum Levels of Zinc, Copper, and Iron with Risk of Metabolic Syndrome.
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Association of copper exposure with metabolic syndrome: a dose-response meta-analysis.BMC endocrine disorders · 2026Pooled it
- Effect of Cashew Nut Consumption on Biomarkers of Copper and Zinc Status in Adolescents with Obesity: A Randomized Controlled Trial.Nutrients · 2024Trial
- Association Between Dietary Copper Intake and Incident Metabolic Syndrome in Chinese Adults: A Discrete-Time Hazard Model Analysis.Nutrients · 2026Article
- Beneficial Role of Zinc in Metabolic Syndrome: Understanding the Underlying Pathophysiological Mechanisms.Current medicinal chemistry · 2026Review
- The association of dietary fiber, antioxidants, and micronutrients with metabolic syndrome among fishermen and farmers: The mediating role of physical activity (A case-control study).Journal of education and health promotion · 2026Article
- Reduced serum iron levels are associated with metabolic dysfunction and sex-specific characteristics.Internal and emergency medicine · 2026Article
- Association of heavy metals and bio-elements blood level with metabolic syndrome: a systematic review and meta-analysis of observational studies.Journal of diabetes and metabolic disorders · 2024Review
- Iron homeostasis and insulin sensitivity: unraveling the complex interactions.Reviews in endocrine & metabolic disorders · 2024Review
- Metabolic Derangement of Essential Transition Metals and Potential Antioxidant Therapies.International journal of molecular sciences · 2024Review
- Additive manufacturing of degradable metallic scaffolds for material-structure-driven diabetic maxillofacial bone regeneration.Bioactive materials · 2024Article
- Overweight, Obesity, Hypertriglyceridemia, and Insulin Resistance Are Positively Associated with High Serum Copper Levels in Mexican Adults.Metabolites · 2024Article
- Article
- Trace element zinc metabolism and its relation to tumors.Frontiers in endocrinology · 2024Review
- Serum copper and obesity among healthy adults in the National Health and Nutrition Examination Survey.PloS one · 2024Article
- Age-dependent interaction between serum zinc and triglyceride-glucose index among American adults: National Health and Nutrition Examination Survey.Frontiers in nutrition · 2024Article
- Associations of VEGF-A-Related Variants with Adolescent Cardiometabolic and Dietary Parameters.Nutrients · 2023Article
- Parasitic infections as potential risk factors for attention deficit hyperactivity disorder (ADHD) in children.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Vanadium, cobalt, zinc, and rubidium are associated with markers of inflammation and oxidative stress in a Greek population with obesity.Frontiers in endocrinology · 2023Article
- Evaluation of Trace Elements Levels and Construction of Auxiliary Prediction Model in Patients with Diabetes Ketoacidosis in Type 1 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between serum concentrations of zinc, copper, or iron and the risk of metabolic syndrome are inconclusive. Therefore, we conduct a case-control study to explore the relationship between serum levels of zinc, copper, or iron and metabolic syndrome as well as each metabolic factor and insulin resistance. We enrolled 1165 adults, aged ≥ 40 (65.8 ± 10) years in a hospital-based population to compare the serum levels of zinc, copper, and iron between subjects with and without metabolic syndrome by using multivariate logistic regression analyses. The least square means were computed by general linear models to compare serum concentrations of zinc, copper, and iron in relation to the number of metabolic factors. The mean serum concentrations of zinc, copper, and iron were 941.91 ± 333.63 μg/L, 1043.45 ± 306.36 μg/L, and 1246.83 ± 538.13 μg/L, respectively. The odds ratios (ORs) of metabolic syndrome for the highest versus the lowest quartile were 5.83 (95% CI: 3.35-10.12;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.