Evidence map›Paper›PMID 33562295›Full record

ArticleNutrients2021

Circulating Adiponectin and Its Association with Metabolic Traits and Type 2 Diabetes: Gene-Diet Interactions Focusing on Selected Gene Variants and at the Genome-Wide Level in High-Cardiovascular Risk Mediterranean Subjects.

Oscar Coltell, Carolina Ortega-Azorín, Jose V Sorlí, Olga Portolés, Eva M Asensio, Carmen Saiz, Rocío Barragán, Ramon Estruch, Dolores Corella

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  7. The Plasma Levels of Protein Adiponectin (Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Oscar ColtellDepartment of Computer Languages and Systems, Universitat Jaume I, 12071 Castellón, Spain.ORCID 0000-0002-4518-8495
Carolina Ortega-AzorínCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0001-6719-9358
Jose V SorlíCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-0130-2006
Olga PortolésCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Eva M AsensioCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Carmen SaizCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-9294-4716
Rocío BarragánCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0001-8072-3791
Ramon EstruchCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0003-1260-4445
Dolores CorellaCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-2366-4104
Universitat de València · ESInstituto de Salud Carlos III · ESUniversitat Jaume I · ES

Funding

Fundació La Marató de TV3 538/U/2016Generalitat Valenciana APOSTD/2019/136Generalitat Valenciana PROMETEO 17/2017Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) CIBER 06/03Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI06/1326Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI13/00728Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI16/00366Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI19/00781Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) SAF2016-80532-RThe Rei Jaume I Award for Medical Research 2018 Medical Research 2018University Jaume I P1-1B2013-54 and COGRUP/2016/06
6 · The paper itself

Abstract

Adiponectin is gaining renewed interest since, in addition to its possible protective role against insulin resistance and arteriosclerosis, recent studies suggest other additional favorable effects. However, the influence of gene-diet interactions on plasma adiponectin levels is still little understood. We analyzed the association between plasma adiponectin levels and various metabolic traits in a high-cardiovascular risk Mediterranean population, as well as the genetic effect of four candidate single-nucleotide polymorphisms (SNPs) in the adiponectin gene (

Indexed as

Diet, MediterraneanGenome-Wide Association StudyPolymorphism, Single NucleotideAdiponectinAgedAged, 80 and overCardiovascular DiseasesDiabetes Mellitus, Type 2FemaleHumansMaleMetabolic SyndromeMiddle AgedRiskVesicular Transport ProteinsAdiponectinVAT1 protein, humanVesicular Transport Proteinsadiponectinbody mass indexgene–diet interactionsgeneticsgenome-wide association studyMediterranean dietplasma lipidspolymorphismstype 2 diabetes

Identifiers

PMID33562295
PMCPMC7914877
OpenAlexW3128910052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.