Evidence map›Paper›PMID 33562186›Full record

ArticleBrain sciences2021

Ouabain-Induced Gene Expression Changes in Human iPSC-Derived Neuron Culture Expressing Dopamine and cAMP-Regulated Phosphoprotein 32 and GABA Receptors.

Alexander V Lopachev, Maria A Lagarkova, Olga S Lebedeva, Margarita A Ezhova, Rogneda B Kazanskaya, Yulia A Timoshina, Anastasiya V Khutorova, Evgeny E Akkuratov, Tatiana N Fedorova, Raul R Gainetdinov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Ouabain-NaNeurochemical research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Alexander V LopachevLaboratory of Clinical and Experimental Neurochemistry, Research Center of Neurology, 125367 Moscow, Russia.
Maria A LagarkovaLaboratory of Cell Biology, Federal Research and Clinical Center of Physical-Chemical Medicine Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-9594-1134
Olga S LebedevaLaboratory of Cell Biology, Federal Research and Clinical Center of Physical-Chemical Medicine Federal Medical Biological Agency, 119435 Moscow, Russia.
Margarita A EzhovaLaboratory of Plant Genomics, Institute for Information Transmission Problems of the Russian Academy of Sciences, 127051 Moscow, Russia.
Rogneda B KazanskayaBiological Department, Saint Petersburg State University, 199034 St. Petersburg, Russia.
Yulia A TimoshinaLaboratory of Clinical and Experimental Neurochemistry, Research Center of Neurology, 125367 Moscow, Russia.
Anastasiya V KhutorovaLaboratory of Clinical and Experimental Neurochemistry, Research Center of Neurology, 125367 Moscow, Russia.
Evgeny E AkkuratovDepartment of Applied Physics, Royal Institute of Technology, Science for Life Laboratory, 171 65 Stockholm, Sweden.
Tatiana N FedorovaLaboratory of Clinical and Experimental Neurochemistry, Research Center of Neurology, 125367 Moscow, Russia.
Raul R GainetdinovInstitute of Translational Biomedicine and Saint Petersburg University Hospital, Saint Petersburg State University, 199034 St. Petersburg, Russia.
Federal Medical-Biological Agency · RULomonosov Moscow State University · RUResearch Center of Neurology · RUSt Petersburg University · RUScience for Life Laboratory · SESkolkovo Institute of Science and Technology · RU

Funding

Russian Foundation for Basic Research 18-04-01321Saint Petersburg State University 51143531
6 · The paper itself

Abstract

Cardiotonic steroids (CTS) are specific inhibitors and endogenous ligands of a key enzyme in the CNS-the Na

Indexed as

cardiotonic steroidsdopamineGABAgene expressioniPSCNa+,K+-ATPaseneuronsouabainRNA-seqtranscriptome

Identifiers

PMID33562186
PMCPMC7915459
OpenAlexW3128213808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.