Evidence map›Paper›PMID 33562155›Full record

ArticlePharmaceutics2021

Dexamethasone PLGA Microspheres for Sub-Tenon Administration: Influence of Sterilization and Tolerance Studies.

Deyanira Barbosa-Alfaro, Vanessa Andrés-Guerrero, Ivan Fernandez-Bueno, María Teresa García-Gutiérrez, Esther Gil-Alegre, Irene Teresa Molina-Martínez, José Carlos Pastor-Jimeno, Rocío Herrero-Vanrell, Irene Bravo-Osuna

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Long-Acting Ocular Injectables: Are We Looking In The Right Direction?Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Deyanira Barbosa-AlfaroInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.
Vanessa Andrés-GuerreroInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0157-1932
Ivan Fernandez-BuenoThematic Research Network in Ophthalmology (Oftared) Carlos III National Institute of Health, 28040 Madrid, Spain.ORCID 0000-0003-3380-4040
María Teresa García-GutiérrezInstituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, 47011 Valladolid, Spain.
Esther Gil-AlegreInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.
Irene Teresa Molina-MartínezInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-9157-571X
José Carlos Pastor-JimenoThematic Research Network in Ophthalmology (Oftared) Carlos III National Institute of Health, 28040 Madrid, Spain.ORCID 0000-0001-5934-7306
Rocío Herrero-VanrellInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.
Irene Bravo-OsunaInnovation, Therapy and Pharmaceutical Development in Ophthalmology (InnOftal) Research Group, UCM 920415, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-3133-7872
Universidad Complutense de Madrid · ESUniversidad de Valladolid · ES

Funding

Complutense University of Madrid UCM-920415CONACYT (Mexico) CONACYTJunta de Castilla y León Junta de Castilla y LeónSpanish Ministry of Education and Ministry of Science and Technology MAT 2017-83858-C2-1-RThematic Research Network in Ophthalmology (Oftared) Carlos III National Institute of Health RD16/0008/0001, RD16/0008/0004, RD16/0008/0009
6 · The paper itself

Abstract

Many diseases affecting the posterior segment of the eye require repeated intravitreal injections with corticosteroids in chronic treatments. The periocular administration is a less invasive route attracting considerable attention for long-term therapies. In the present work, dexamethasone-loaded poly(lactic-

Indexed as

dexamethasonegamma sterilizationmicrospheresophthalmologyperiocular administrationpoly(lactic-co-glycolic) acidtolerance

Identifiers

PMID33562155
PMCPMC7915986
OpenAlexW3127345941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.