Evidence map›Paper›PMID 33562153›Full record

ReviewMarine drugs2021

Antiviral Potential of Algal Metabolites-A Comprehensive Review.

António Pagarete, Ana Sofia Ramos, Pål Puntervoll, Michael J Allen, Vítor Verdelho

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Antimicrobial and anti-biofilm activity of silver nanoparticles biosynthesized with Cystoseira algae extracts.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Virucidal activity of microalgae extracts harvested during phycoremediation of swine wastewater.Environmental science and pollution research international · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

António PagareteEdificio TecLabs, Faculdade de Ciências, Biosystems and Integrative Sciences Institute (BioISI), Universidade de Lisboa, Campus da FCUL, Campo Grande, 1749-016 Lisboa, Portugal.ORCID 0000-0003-1347-0282
Ana Sofia RamosInstitute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Pål PuntervollNORCE Norwegian Research Centre, Postboks 22 Nygårdstangen, 5838 Bergen, Norway.ORCID 0000-0003-0093-7816
Michael J AllenPlymouth Marine Laboratory, Plymouth PL1 3DH, UK.ORCID 0000-0001-8504-7171
Vítor VerdelhoAlgae for Future, SA, Rua Eng. Clément Dumoulin Business Park, 2625-106 Póvoa de Santa Iria, Portugal.
NORCE Research AS · NOUniversity of Exeter · GBUniversity of Lisbon · PTUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, algae have stimulated significant economic interest particularly as a source of fertilizers, feeds, foods and pharmaceutical precursors. However, there is increasing interest in exploiting algal diversity for their antiviral potential. Here, we present an overview of 50-years of scientific and technological developments in the field of algae antivirals. After bibliometric analysis of 999 scientific references, a survey of 16 clinical trials and analysis of 84 patents, it was possible to identify the dominant algae, molecules and viruses that have been shaping and driving this promising field of research. A description of the most promising discoveries is presented according to molecule class. We observed a diverse range of algae and respective molecules displaying significant antiviral effects against an equally diverse range of viruses. Some natural algae molecules, like carrageenan, cyanovirin or griffithsin, are now considered prime reference molecules for their outstanding antiviral capacity. Crucially, while many algae antiviral applications have already reached successful commercialization, the large spectrum of algae antiviral capacities already identified suggests a strong potential for future expansion of this field.

Indexed as

AgricultureAntiviral AgentsAquacultureBacterial ProteinsClinical Trials as TopicDiterpenesLectinsMembrane ProteinsMicroalgaePlant LectinsPolysaccharidesSeaweedAntiviral AgentsBacterial ProteinsDiterpenesfucoidangriffithsin protein, GriffithsiaLectinsMembrane ProteinsPlant LectinsPolysaccharidesscytovirin protein, S variumalgaecoronavirusescyanobacteriaHIVimmunomodulatory effectslectinssulfated polysaccharides

Identifiers

PMID33562153
PMCPMC7914423
OpenAlexW3128441247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.