Evidence map›Paper›PMID 33562128›Full record

ReviewPharmaceutics2021

Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties.

Umile Gianfranco Spizzirri, Francesca Aiello, Gabriele Carullo, Anastasia Facente, Donatella Restuccia

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  8. Review
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  11. Article
  12. Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  13. Article
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  19. Article
  20. Utilisation ofFuture journal of pharmaceutical sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Umile Gianfranco SpizzirriDepartment of Pharmacy, Health and Nutritional Sciences Department of Excellence 2018-2022, University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy.ORCID 0000-0002-5447-9497
Francesca AielloDepartment of Pharmacy, Health and Nutritional Sciences Department of Excellence 2018-2022, University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy.ORCID 0000-0001-6846-5582
Gabriele CarulloDepartment of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0002-1619-3295
Anastasia FacenteDepartment of Pharmacy, Health and Nutritional Sciences Department of Excellence 2018-2022, University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy.
Donatella RestucciaDepartment of Pharmacy, Health and Nutritional Sciences Department of Excellence 2018-2022, University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy.ORCID 0000-0002-3415-3828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Site-Specific release of active molecules with antimicrobial activity spurred the interest in the development of innovative polymeric nanocarriers. In the preparation of polymeric devices, nanotechnologies usually overcome the inconvenience frequently related to other synthetic strategies. High performing nanocarriers were synthesized using a wide range of starting polymer structures, with tailored features and great chemical versatility. Over the last decade, many antimicrobial substances originating from plants, herbs, and agro-food waste by-products were deeply investigated, significantly catching the interest of the scientific community. In this review, the most innovative strategies to synthesize nanodevices able to release antimicrobial natural extracts were discussed. In this regard, the properties and structure of the starting polymers, either synthetic or natural, as well as the antimicrobial activity of the biomolecules were deeply investigated, outlining the right combination able to inhibit pathogens in specific biological compartments.

Indexed as

agro-food-wastesantimicrobial agentsnanotechnologiesplant extractspolymeric nanocarriers

Identifiers

PMID33562128
PMCPMC7915176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.