Evidence map›Paper›PMID 33562124›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Cryo-Electron Tomography of Candida glabrata Plasma Membrane Proteins.

Cristina Jiménez-Ortigosa, Jennifer Jiang, Muyuan Chen, Xuyuan Kuang, Kelley R Healey, Paul Castellano, Nikpreet Boparai, Steven J Ludtke, David S Perlin, Wei Dai

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Correction: Jiménez-Ortigosa et al. Cryo-Electron Tomography ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Analysis of the Localization ofInternational journal of molecular sciences · 2023
    Article
  9. Computational methods forFrontiers in cellular and infection microbiology · 2023
    Review
  10. Caspofungin resistance in Candida albicans: genetic factors and synergistic compounds for combination therapies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Cristina Jiménez-OrtigosaHackensack Meridian Health-Center for Discovery and Innovation, 111 Ideation Way, Nutley, NJ 07110, USA.
Jennifer JiangDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08854, USA.ORCID 0000-0001-6302-5916
Muyuan ChenDepartment of Biochemistry and Molecular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Xuyuan KuangDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08854, USA.
Kelley R HealeyDepartment of Biology, William Paterson University, 300 Pompton Road, Wayne, NJ 07470, USA.ORCID 0000-0001-5636-256X
Paul CastellanoDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08854, USA.
Nikpreet BoparaiDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08854, USA.ORCID 0000-0003-4424-1001
Steven J LudtkeDepartment of Biochemistry and Molecular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.ORCID 0000-0002-1903-1574
David S PerlinHackensack Meridian Health-Center for Discovery and Innovation, 111 Ideation Way, Nutley, NJ 07110, USA.
Wei DaiDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08854, USA.ORCID 0000-0003-3032-3399
Rutgers, The State University of New Jersey · USBaylor College of Medicine · USHackensack Meridian Health · USWilliam Paterson University · US

Funding

SUPPORT AND DEVELOPMENT OF EMAN FOR ELECTRON MICROSCOPY IMAGE PROCESSINGR01GM080139 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI LUDTKE, STEVEN J · 2006 to 2022
$5.4M
Midwest Consortium for High Resolution Cryoelectron MicroscopyU24GM116789 · NIGMS · PURDUE UNIVERSITY · PI BULLITT, ESTHER, DAI, WEI · 2017 to 2021
$3.5M
National Institutes of Health Midwest Consortium for High Resolution Cryo-electron Microscopy U24 GM116789-01A1NIGMS NIH HHS U24 GM116789NIH HHS AI109025NIH HHS P011030036319NIH HHS R01GM080139
6 · The paper itself

Abstract

Fungal plasma membrane proteins have long been recognized as targets for the development of antifungal agents. Despite recent progress in experimental approaches and computational structural predictions, our knowledge of the structural dynamics and spatial distribution of these membrane proteins in the context of their native lipid environment remains limited. By applying cryo-electron tomography (cryoET) and subtomogram analysis, we aim to characterize the structural characteristics and spatial distribution of membrane proteins present in

Indexed as

Candida glabratacryo-electron tomography (cryoET)fungal membrane proteins

Identifiers

PMID33562124
PMCPMC7914498
OpenAlexW3126195247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.