Evidence map›Paper›PMID 33562115›Full record

ArticleJournal of clinical medicine2021

A Novel Nutraceutical Formulation Can Improve Motor Activity and Decrease the Stress Level in a Murine Model of Middle-Age Animals.

Dimitris Tsoukalas, Ovidiu Zlatian, Mihaela Mitroi, Elisavet Renieri, Aristidis Tsatsakis, Boris Nikolaevich Izotov, Florin Burada, Simona Sosoi, Emilia Burada, Ana Maria Buga and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  14. The Pharmacological Activities ofOxidative medicine and cellular longevity · 2022
    Review
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  17. Oxidative medicine and cellular longevity · 2022
    Review
  18. Recent updates on anticancer mechanisms of polyphenols.Frontiers in cell and developmental biology · 2022
    Review
  19. Reversal of brain aging by targeting telomerase: A nutraceutical approach.International journal of molecular medicine · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 4 countries.

Dimitris TsoukalasDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ovidiu ZlatianDepartment of Microbiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mihaela MitroiENT Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Elisavet RenieriLaboratory of Toxicology and Forensic Sciences, Medical School, University of Crete, 71003 Heraklion, Greece.
Aristidis TsatsakisLaboratory of Toxicology and Forensic Sciences, Medical School, University of Crete, 71003 Heraklion, Greece.ORCID 0000-0003-3824-2462
Boris Nikolaevich IzotovDepartment of Analytical and Forensic Medical Toxicology, Sechenov University, 119991 Moscow, Russia.
Florin BuradaHuman Genomics Laboratory, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Simona SosoiHuman Genomics Laboratory, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Emilia BuradaDepartment of Physiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ana Maria BugaDepartment of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-0082-6956
Ion RogoveanuDepartment of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-8162-5955
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-1523-9116
University of Medicine and Pharmacy of Craiova · ROUniversity of Crete · GRSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ageing is a genetically programmed physiological process that is modulated by numerous environmental factors, associated with decreasing physiological function, decreasing reproductive rate and increasing age-related mortality rate. Maintaining mobility performance and physical function in the elderly is the main objective of the successful ageing concept. In this study, we aimed to evaluate the beneficial effect of a novel nutraceutical formulation containing

Indexed as

ageinganxiety levelsCentella asiatica L.motor performancevitamin Cvitamin Dzinc

Identifiers

PMID33562115
PMCPMC7915416
OpenAlexW3128371550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.