Evidence map›Paper›PMID 33562108›Full record

ReviewCells2021

Human Genetic Variation Influences Enteric Fever Progression.

Pei Yee Ma, Jing En Tan, Edd Wyn Hee, Dylan Wang Xi Yong, Yi Shuan Heng, Wei Xiang Low, Xun Hui Wu, Christy Cletus, Dinesh Kumar Chellappan, Kyan Aung and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Risk Factors for Typhoid Fever: Systematic Review.JMIR public health and surveillance · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Revisiting PersistentPathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Pei Yee MaSchool of Postgraduate Studies, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia.
Jing En TanSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Edd Wyn HeeSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Dylan Wang Xi YongSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Yi Shuan HengSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Wei Xiang LowSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Xun Hui WuSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.ORCID 0000-0002-5967-5059
Christy CletusSchool of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
Dinesh Kumar ChellappanDepartment of Life Sciences, International Medical University, Kuala Lumpur 57000, Malaysia.ORCID 0000-0001-5567-6663
Kyan AungDepartment of Pathology, International Medical University, Kuala Lumpur 57000, Malaysia.
Chean Yeah YongDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0002-0842-6386
Yun Khoon LiewDepartment of Life Sciences, International Medical University, Kuala Lumpur 57000, Malaysia.
IMU University · MYUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the 21st century, enteric fever is still causing a significant number of mortalities, especially in high-risk regions of the world. Genetic studies involving the genome and transcriptome have revealed a broad set of candidate genetic polymorphisms associated with susceptibility to and the severity of enteric fever. This review attempted to explain and discuss the past and the most recent findings on human genetic variants affecting the progression of

Indexed as

Disease ProgressionGenetic VariationBiomarkersHumansImmunity, InnateSample SizeTyphoid FeverBiomarkersenteric feverhuman genetic variantsSalmonella typhoidal species

Identifiers

PMID33562108
PMCPMC7915608
OpenAlexW3128763543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.