ArticlePathogens (Basel, Switzerland)2021
African Swine Fever Laboratory Diagnosis-Lessons Learned from Recent Animal Trials.
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Early Detection and Long-Term Monitoring as a Strategy for African Swine Fever Outbreak Control and a Comparative Study on the Reproductive Performance of Convalescent and Naïve Sows in a Commercial Farm in Thailand.Animals : an open access journal from MDPI · 2026Article
- Molecular identification and phylogenetic profiling of African swine fever virus in Indonesia during 2021-2025 based on theVeterinary world · 2026Article
- Article
- Successful Inactivation of High-Consequence Pathogens in PrimeStore Molecular Transport Media.Viruses · 2025Article
- Emergence and Control of African Swine Fever.Pathogens (Basel, Switzerland) · 2025Article
- Article
- Evaluation of Selective Culling as a Containment Strategy for African Swine Fever at a Vietnamese Sow Farm.Pathogens (Basel, Switzerland) · 2024Article
- Establishment of a Suitable Diagnostic Workflow to Ensure Sensitive Detection of African Swine Fever Virus Genome in Porcine Semen.Pathogens (Basel, Switzerland) · 2024Article
- Generation of High-Quality African Swine Fever Virus Complete Genome from Field Samples by Next-Generation Sequencing.Viruses · 2024Article
- Stability of GenotubeViruses · 2024Article
- A suitable sampling strategy for the detection of African swine fever virus in living and deceased pigs in the field: a retrospective study.Frontiers in veterinary science · 2024Article
- Functional Landscape of African Swine Fever Virus-Host and Virus-Virus Protein Interactions.Viruses · 2023Review
- Comparison of diaphragm meat juice and muscle swab samples to spleen and spleen swab samples for the detection of African swine fever viral nucleic acid.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023Article
- Innovative Research Offers New Hope for Managing African Swine Fever Better in Resource-Limited Smallholder Farming Settings: A Timely Update.Pathogens (Basel, Switzerland) · 2023Review
- Modeling the accuracy of a novel PCR and antibody ELISA for African swine fever virus detection using Bayesian latent class analysis.Frontiers in veterinary science · 2023Article
- Artificial Insemination as an Alternative Transmission Route for African Swine Fever Virus.Pathogens (Basel, Switzerland) · 2022Article
- A practical guide for strategic and efficient sampling in African swine fever-affected pig farms.Transboundary and emerging diseases · 2022Article
- Utilizing blood filter paper and ear punch samples for the detection of rabbit hemorrhagic disease virus 2 by RT-rtPCR.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Development of a ladder-shape melting temperature isothermal amplification (LMTIA) assay for detection of African swine fever virus (ASFV).Journal of veterinary science · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
African swine fever virus (ASFV) causes a hemorrhagic disease in pigs with high socio-economic consequences. To lower the impact of disease incursions, early detection is crucial. In the context of experimental animal trials, we evaluated diagnostic workflows for a high sample throughput in active surveillance, alternative sample matrices for passive surveillance, and lateral flow devices (LFD) for rapid testing. We could demonstrate that EDTA blood is significantly better suited for early ASFV detection than serum. Tissues recommended by the respective diagnostic manuals were in general comparable in their performance, with spleen samples giving best results. Superficial lymph nodes, ear punches, and different blood swabs were also evaluated as potential alternatives. In summary, all matrices yielded positive results at the peak of clinical signs and could be fit for purpose in passive surveillance. However, weaknesses were discovered for some matrices when it comes to the early phase of infection or recovery. The antigen LFD showed variable results with best performance in the clinical phase. The antibody LFD was quite comparable with ELISA systems. Concluding, alternative approaches are feasible but have to be embedded in control strategies selecting test methods and sample materials following a "fit-for-purpose" approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.