ReviewJournal of clinical medicine2021
Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Development and validation of a machine learning-based prediction model for thrombocytopenia following cardiopulmonary bypass.Scientific reports · 2026Article
- Prognostic impact of persistent versus transient sepsis-associated thrombocytopenia in multicohort data.iScience · 2025Article
- Effects of improved ultrafiltration on serum level of IL-6 and TNF-a, HCT, and cardiopulmonary function in patients with extracorporeal circulation in valve replacement.Journal of medical biochemistry · 2025Article
- Initial Thrombocyte Concentrate Transfusion in Woman with Chronic Immune Thrombocytopenia Purpura (ITP) Who Underwent Mitral Valve Replacement Surgery: A Case Report.The American journal of case reports · 2023Article
- Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass.Artificial organs · 2022Review
- Effect of Platelet Transfusions on Extracorporeal Life Support Oxygenator's Function.Frontiers in pediatrics · 2022Article
- Article
- Clot Retraction: Cellular Mechanisms and Inhibitors, Measuring Methods, and Clinical Implications.Biomedicines · 2021Review
- Special Issue: "The Latest Clinical Advances in Thrombocytopenia".Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thrombocytopenia and impaired platelet function are known as intrinsic drawbacks of cardiac surgery and extracorporeal life supports (ECLS). A number of different factors influence platelet count and function including the inflammatory response to a cardiopulmonary bypass (CPB) or to ECLS, hemodilution, hypothermia, mechanical damage and preoperative treatment with platelet-inhibiting agents. Moreover, although underestimated, heparin-induced thrombocytopenia is still a hiccup in the perioperative management of cardiac surgical and, above all, ECLS patients. Moreover, recent investigations have highlighted how platelet disorders also affect patients undergoing biological prosthesis implantation. Though many hypotheses have been suggested, the mechanism underlying thrombocytopenia and platelet disorders is still to be cleared. This narrative review aims to offer clinicians a summary of their major causes in the cardiac surgery setting.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.