ArticleAnimal bioscience2021
Effects of Artemisia argyi flavonoids on growth performance and immune function in broilers challenged with lipopolysaccharide.
Article in Animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Dietary α-Mangostin alleviates lipopolysaccharide-induced stress and enhances growth performance in broilers via improved intestinal immunity and integrity.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- A mugwort-based Chinese herbal mixture of five herbs improved oviduct health in laying hens under LPS challenge.Poultry science · 2026Article
- Effects of Artemisia argyi powder on growth performance, meat quality, meat flavor and intestinal health of ducks.Poultry science · 2026Article
- The additive from co-fermented edible plants and probiotics improved calves' growth performance and health by regulating antioxidant and gastrointestinal-microbiota.Animal bioscience · 2026Article
- Effect of Alligator Weed (Animals : an open access journal from MDPI · 2025Article
- Transcriptome and metabolome analyses revealed the main profiles contributing the mild aroma characteristics ofFrontiers in plant science · 2025Article
- Jumbo quail responses to diets containing incremental levels of apple (Malus domestica Borkh) pomace.Tropical animal health and production · 2024Article
- Effects of Ferulic Acid on Lipopolysaccharide-Induced Oxidative Stress and Gut Microbiota Imbalance in Linwu Ducks.Antioxidants (Basel, Switzerland) · 2024Article
- The effects ofVeterinary world · 2024Article
- Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response.Animals : an open access journal from MDPI · 2024Review
- Effects of Aspirin Eugenol Ester on Liver Oxidative Damage and Energy Metabolism in Immune-Stressed Broilers.Antioxidants (Basel, Switzerland) · 2024Article
- The impact of dietary supplementation of Quercetagetin on growth, antioxidant capacity, and gut microbiota of diquat-challenged broilers.Frontiers in microbiology · 2024Article
- Oxidative stress model of lipopolysaccharide combined with thrombin inducing in broiler chicks.Frontiers in veterinary science · 2024Article
- Effects ofFrontiers in physiology · 2024Article
- Effects ofAnimals : an open access journal from MDPI · 2023Article
- Article
- Article
- Effect of Dietary Chlorogenic Acid on Growth Performance, Antioxidant Function, and Immune Response of Broiler Breeders under Immune Stress and Stocking Density Stress.Veterinary sciences · 2022Article
- Effects of Total Flavonoids ofAntioxidants (Basel, Switzerland) · 2022Article
- Effect of Immune Stress on Growth Performance and Immune Functions of Livestock: Mechanisms and Prevention.Animals : an open access journal from MDPI · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveThis research aimed to study the effects of Artemisia argyi flavonoids (AAF) supplemented in diets on the growth performance and immune function of broiler chickens challenged with lipopolysaccharide (LPS).
methodsA total of one hundred and ninety-two 1-d-old broiler chicks were assigned into 4 treatment groups, which were, respectively, fed a basal diet (control), fed a diet with 750 mg/kg AAF, fed a basal diet, and challenged with LPS, fed a diet with 750 mg/kg AAF, and challenged with LPS. Each treatment had six pens with 8 chicks per pen. On days 14, 16, 18, 20 (stress phase I) and 28, 30, 32, 34 (stress phase II), broilers were injected with LPS (500 μg/kg body weight) or an equivalent amount of saline.
resultsThe results demonstrated that dietary AAF significantly improved the body weight (d 21) and alleviated the decrease of average daily gain in broilers challenged with LPS on d 21 and d 35 (p<0.05). Dietary AAF increased bursa fabricius index, and dramatically attenuated the elevation of spleen index caused by LPS on d 35 (p<0.05). Furthermore, serum interleukin-6 (IL-6) concentration decreased with AAF supplementation on d 21 (p<0.05). Diet treatment and LPS challenge exhibited a significant interaction for the concentration of IL-1β (d 21) and IL-6 (d 35) in serum (p<0.05). Additionally, AAF supplementation mitigated the increase of IL-1β, IL-6 in liver and spleen induced by LPS on d 21 and 35 (p<0.05). This study also showed that AAF supplementation significantly reduced the expression of IL-1β (d 21) and nuclear transcription factor kappa-B p65 (d 21 and 35) in liver (p<0.05), and dietary AAF and LPS treatment exhibited significant interaction for the gene expression of IL-6 (d 21), toll like receptor 4 (d 35) and myeloid differentiation factor 88 (d 35) in spleen (p<0.05).
conclusionIn conclusion, AAF could be used as a potential natural immunomodulator to improve growth performance and alleviate immune stress in broilers challenged with LPS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.