Evidence map›Paper›PMID 33561807›Full record

ArticleArchives of oral biology2021

P2Y

Kimberly J Jasmer, Lucas T Woods, Kevin Muñoz Forti, Adam L Martin, Jean M Camden, Marco Colonna, Gary A Weisman

Open access · greenAbstract read
In one paragraph

Article in Archives of oral biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. P2YInternational journal of molecular sciences · 2025
    Review
  2. Review
  3. Therapeutic potential for P2YPurinergic signalling · 2023
    Review
  4. Article
  5. Purinergic Signaling in Oral Tissues.International journal of molecular sciences · 2022
    Review
  6. Early Dry Eye Disease Onset in a NOD.H-2h4 Mouse Model of Sjögren's Syndrome.Investigative ophthalmology & visual science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kimberly J JasmerDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA. Electronic address: JasmerK@missouri.edu.
Lucas T WoodsDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA.
Kevin Muñoz FortiDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA.
Adam L MartinDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA.
Jean M CamdenDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA.
Marco ColonnaDepartment of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO, 63110, USA.
Gary A WeismanDepartment of Biochemistry and Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO, 65211-7310, USA.
University of Missouri · USWashington University in St. Louis · US

Funding

VIP RECEPTORS AND SUBMANDIBULAR GLAND FUNCTIONR01DE007389 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 1988 to 2020
$7.6M
The role of TGFbeta in development and function of salivary gland innate lymphoid cellsR01DE025884 · NIDCR · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, WEISMAN, GARY ANDREW · 2017 to 2021
$3.5M
Targeting P2 Receptors to Restore Salivary and Lacrimal Gland Function in Sjogren's SyndromeR01DE029833 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 2021 to 2025
$3.2M
NIDCR NIH HHS R01 DE007389NIDCR NIH HHS R01 DE025884NIDCR NIH HHS R01 DE029833
6 · The paper itself

Abstract

objectiveSjögren's syndrome (SS) is a chronic autoimmune exocrinopathy characterized by lymphocytic infiltration of the salivary and lacrimal glands and decreased saliva and tear production. Previous studies indicate that the G protein-coupled P2Y

designFemale 4.5 month old NOD.H-2

resultsIntraperitoneal injection, but not localized intraglandular administration, of AR-C118925 significantly enhanced carbachol-induced salivation and reduced lymphocytic foci and immune cell markers in SMGs of 5 month old NOD.H-2

conclusionOur findings suggest that the P2Y

Indexed as

SialadenitisSjogren's SyndromeAnimalsDisease Models, AnimalFemaleMiceMice, Inbred C57BLMice, Inbred NODSubmandibular GlandAlarminsAutoimmune diseaseB lymphocytesNucleotidePurinergic receptorSjögren’s syndrome

Identifiers

PMID33561807
PMCPMC7958986
OpenAlexW3129174687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.