Evidence map›Paper›PMID 33561671›Full record

ArticleEnvironment international2021

Ubiquitous atmospheric contamination by tobacco smoke: Nicotine and a new marker for tobacco smoke-derived particulate matter, nicotelline.

Noel J Aquilina, Christopher M Havel, Polly Cheung, Roy M Harrison, Kin-Fai Ho, Neal L Benowitz, Peyton Jacob Iii

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Tobacco-specific and combustion pollutants in settled house dust in Malta.Journal of environmental exposure assessment · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 5 countries.

Noel J AquilinaDepartment of Chemistry, University of Malta, Msida MSD 2080, Malta; Division of Cardiology, Clinical Pharmacology Program, Department of Medicine, University of California, San Francisco, CA 94143, United States. Electronic address: noel.aquilina@um.edu.mt.
Christopher M HavelDivision of Cardiology, Clinical Pharmacology Program, Department of Medicine, University of California, San Francisco, CA 94143, United States.
Polly CheungDivision of Cardiology, Clinical Pharmacology Program, Department of Medicine, University of California, San Francisco, CA 94143, United States.
Roy M HarrisonDivision of Environmental Health and Risk Management, School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Kin-Fai HoThe Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China.
Neal L BenowitzDivision of Cardiology, Clinical Pharmacology Program, Department of Medicine, University of California, San Francisco, CA 94143, United States.
Peyton Jacob IiiDivision of Cardiology, Clinical Pharmacology Program, Department of Medicine, University of California, San Francisco, CA 94143, United States.
University of California, San Francisco · USChinese University of Hong Kong · HKUniversity of Birmingham · GB

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON, JONES, REESE T. · 1999 to 2024
$17.1M
Liquid Chromatograph-Triple Quadrupole Mass SpectrometerS10RR026437 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 2010 to 2010
$448k
NCRR NIH HHS S10 RR026437NIDA NIH HHS P30 DA012393
6 · The paper itself

Abstract

Second Hand Smoke (SHS) has always been primarily linked with indoor pollution. To date nicotine was the favoured marker for SHS alongside measurements of particulate matter (PM) levels. As nicotine is mainly found in the gas-phase and reactive in the outdoor environment it is not ideal as a marker for the SHS-driven particulate component in PM. Nicotelline, a minor tobacco alkaloid that is stable, found almost exclusively in the particle phase and easy to quantify even at low concentrations, is being proposed as a better marker. It is the first study using bisulfate-treated quartz fiber filters to show that airborne nicotine (gas+particle phase) is directly proportional to airborne nicotelline in countries that have different climates. The analytical method developed has been validated to show that the use of untreated filters is suitable for the quantification of nicotelline even at low concentrations. Although nicotelline exhibits a seasonal and geographical variation, this is the first comprehensive study which demonstrates the ubiquitous presence of nicotelline in PM from outdoor air samples collected in the USA (0.1-285.6 pgm

Indexed as

Air Pollution, IndoorTobacco Smoke PollutionDustHong KongNicotineParticulate MatterDustNicotineParticulate MatterTobacco Smoke PollutionAlkaloidAtmospheric markerNicotellineNicotineParticulate matterSecond hand smoke

Identifiers

PMID33561671
PMCPMC7987222
OpenAlexW3129188387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.