Evidence map›Paper›PMID 33561394›Full record

ArticleCancer cell2021

A Malignant Case of Arrested Development: Cancer Cell Dormancy Mimics Embryonic Diapause.

Yu-Hsuan Lin, Hao Zhu

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. A genome-wide association study implicates the olfactory system inbioRxiv : the preprint server for biology · 2025
    Article
  3. Review
  4. Article
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  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yu-Hsuan LinChildren's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hao ZhuChildren's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: hao.zhu@utsouthwestern.edu.

Funding

Improving hepatocellular carcinoma mouse modeling by understanding the malignant potential and biology of liver cell subpopulationsR01CA251928 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ZHU, HAO · 2020 to 2024
$2.7M
NCI NIH HHS R01 CA251928
6 · The paper itself

Abstract

Writing in Cancer Cell and Cell, two groups investigate the nature of dormant cancer cells that persist after chemotherapy. These cells adopt a state that resembles diapause, an evolutionarily conserved adaptation used by embryos to survive inhospitable conditions. Understanding cancer diapause could uncover therapeutic strategies that reduce cancer relapse.

Indexed as

DiapauseNeoplasmsAdaptation, PhysiologicalAnimals

Identifiers

PMID33561394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.