Evidence map›Paper›PMID 33561234›Full record

ArticleG3 (Bethesda, Md.)2021

Chi-miR-130b-3p regulates Inner Mongolia cashmere goat skin hair follicles in fetuses by targeting Wnt family member 10A.

Zhihong Wu, Erhan Hai, Zhengyang Di, Rong Ma, Fangzheng Shang, Min Wang, Lili Liang, Youjun Rong, Jianfeng Pan, Rui Su and 4 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Zhihong WuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Erhan HaiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Zhengyang DiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Rong MaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Fangzheng ShangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Min WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Lili LiangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Youjun RongCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Jianfeng PanCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Rui SuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Zhiying WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Ruijun WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Yanjun ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Jinquan LiEngineering Research Center for Goat Genetics and Breeding, Hohhot 010018, Inner Mongolia Autonomous Region, China.
Inner Mongolia Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of hair follicles (HFs) is dependent on interactions between epithelial cells and dermal fibroblasts, which may play an important role in maintaining the structure of HFs during their development and maturation. Wnt family member 10 (WNT10A) is a hub gene during HF development and maturation that may regulate the proliferation of dermal fibroblasts and epithelial cells through microRNAs (miRNAs) and messenger RNAs (mRNAs) to maintain the structural stability of HFs. In the present study, we confirmed that WNT10A is the target gene of chi-miR-130b-3p by real-time quantitative PCR, western blotting, and a dual-luciferase reporter gene assay. We successfully cultured fetal epithelial cells and dermal fibroblasts using the tissue block attachment method, and Cell Counting Kit-8 (CCK8) results showed that chi-miR-130b-3p regulates epithelial cell and dermal fibroblast proliferation by targeting WNT10A.

Indexed as

Hair FollicleMicroRNAsAnimalsCell ProliferationChinaFetusGoatsMicroRNAscashmere goatchi-miR-130b-3pdevelopmentfibroblast proliferationhair folliclemicroRNAWNT10AWnt family

Identifiers

PMID33561234
PMCPMC8022718
OpenAlexW3128328603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.