Evidence map›Paper›PMID 33561039›Full record

ArticleInternational journal of environmental research and public health2020

INSIDE Project: Individual Air Pollution Exposure, Extracellular Vesicles Signaling and Hypertensive Disorder Development in Pregnancy.

Luca Ferrari, Francesca Borghi, Simona Iodice, Dolores Catelan, Stefano Rossi, Ilaria Giusti, Laura Grisotto, Sabrina Rovelli, Andrea Spinazzè, Rossella Alinovi and 20 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. PMArchives of toxicology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 6 institutions in 1 country.

Luca FerrariEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-0103-2170
Francesca BorghiDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.ORCID 0000-0003-3452-2803
Simona IodiceEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Dolores CatelanDepartment of Statistics, Computer Science and Applications "G. Parenti", Università degli Studi di Firenze, 50134 Florence, Italy.
Stefano RossiCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.ORCID 0000-0003-0346-8410
Ilaria GiustiDepartment of Life, Health and Environmental Sciences, Università degli Studi dell'Aquila, 67100 L'Aquila, Italy.
Laura GrisottoDepartment of Statistics, Computer Science and Applications "G. Parenti", Università degli Studi di Firenze, 50134 Florence, Italy.
Sabrina RovelliDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.ORCID 0000-0002-6403-5101
Andrea SpinazzèDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.ORCID 0000-0003-0371-3164
Rossella AlinoviCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.
Silvana PinelliCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.
Laura CantoneEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Laura DioniEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Benedetta IschiaDepartment of Obstetrics and Gynecology 'L. Mangiagalli', Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Irene RotaCardiovascular Disease Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Jacopo MarianiEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-0584-7481
Federica RotaEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Mirjam HoxhaEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-1251-2647
Giorgia StoppaDepartment of Statistics, Computer Science and Applications "G. Parenti", Università degli Studi di Firenze, 50134 Florence, Italy.
Damiano MonticelliDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.ORCID 0000-0001-9086-2760
Domenico CavalloDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.
Enrico BergamaschiCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.
Marco VicenziCardiovascular Disease Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Nicola PersicoDepartment of Obstetrics and Gynecology 'L. Mangiagalli', Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Annibale BiggeriDepartment of Statistics, Computer Science and Applications "G. Parenti", Università degli Studi di Firenze, 50134 Florence, Italy.ORCID 0000-0003-2343-3346
Andrea CattaneoDepartment of Science and High Technology, Università degli Studi dell'Insubria, 22100 Como, Italy.ORCID 0000-0002-2962-7259
Vincenza DoloDepartment of Life, Health and Environmental Sciences, Università degli Studi dell'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-0424-6676
Michele MiragoliCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.
Paola MozzoniCenter of Excellence for Toxicological Research, Department of Medicine and Surgery, Università degli Studi di Parma, 43121 Parma, Italy.ORCID 0000-0002-6883-8040
Valentina BollatiEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-0370-9598
University of Milan · ITUniversity of Insubria · ITUniversity of Parma · ITUniversity of Florence · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive disorders are common complications during pregnancy (HDP) with substantial public health impact. Acute and chronic particulate matter (PM) exposure during pregnancy increases the risk of HDP, although the underlying molecular mechanisms remain unclear. Extracellular vesicles (EVs) may be the ideal candidates for mediating the effects of PM exposure in pregnancy as they are released in response to environmental stimuli. The INSIDE project aims to investigate this mechanism in pregnancy outcomes. The study population is enrolled at the Fetal Medicine Unit of Fondazione IRCCS Ca'Granda-Ospedale Maggiore Policlinico at 10-14 weeks of gestation. Exposure to PM

Indexed as

Extracellular VesiclesAdultAir PollutantsAir PollutionCross-Sectional StudiesEnvironmental ExposureFemaleHumansHypertension, Pregnancy-InducedParticulate MatterPregnancyAir PollutantsParticulate Matterair pollution exposureextracellular vesicleshypertensive disorder developmentpregnancy

Identifiers

PMID33561039
PMCPMC7731194
OpenAlexW3110421301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.