ArticleThe British journal of radiology2021
The role of contrast-enhanced ultrasound in the diagnosis of malignant non-mass breast lesions and exploration of diagnostic criteria.
Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 33 citations in OpenAlex.
- A Deep Learning Model Integrating Ultrasound Images and Multidimensional Clinical Information for Differentiating Benign and Malignant Non-Mass Lesions.Diagnostics (Basel, Switzerland) · 2026Article
- Progress in Ultrasound Research on Non-Mass Breast Lesions: Definition, Classification, and Differential Diagnosis.Diagnostics (Basel, Switzerland) · 2026Review
- Value of virtual touch tissue imaging quantification in diagnosing breast mass-type lesions and nonmass lesions: a comparative analysis.Quantitative imaging in medicine and surgery · 2025Article
- Multimodal Deep Learning-Based Classification of Breast Non-Mass Lesions Using Gray Scale and Color Doppler Ultrasound.Diagnostics (Basel, Switzerland) · 2025Article
- Approach to Nonmass Lesions on Breast Ultrasound.The Indian journal of radiology & imaging · 2024Review
- Current status and future perspectives of contrast-enhanced ultrasound diagnosis of breast lesions.Journal of medical ultrasonics (2001) · 2024Review
- A risk prediction stratification for non-mass breast lesions, combining clinical characteristics and imaging features on ultrasound, mammography, and MRI.Frontiers in oncology · 2024Article
- Contrast-enhanced ultrasound-guided biopsy of suspicious breast lesions on contrast-enhanced mammography and contrast-enhanced MRI: a case series.Journal of medical ultrasonics (2001) · 2023Article
- Article
- Non-mass Breast Lesions: Could Multimodal Ultrasound Imaging Be Helpful for Their Diagnosis?Diagnostics (Basel, Switzerland) · 2022Article
- Ultrasound classification of non-mass breast lesions following BI-RADS presents high positive predictive value.PloS one · 2022Article
- Deep Neural Architectures for Contrast Enhanced Ultrasound (CEUS) Focal Liver Lesions Automated Diagnosis.Sensors (Basel, Switzerland) · 2021Article
- Application of Multimodal Ultrasound Combined With BI-RADS in Classification and Diagnosis of Non-Mass Breast Lesions.Journal of clinical ultrasound : JCUArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the value of contrast-enhanced ultrasound (CEUS) for diagnosing malignant non-mass breast lesions (NMLs) and to explore the CEUS diagnostic criteria.
methodsA total of 116 patients with 119 NMLs detected by conventional US were enrolled. Histopathological results were used as the reference standard. The enhancement characteristics of NMLs in CEUS were compared between malignant and benign NMLs. The CEUS diagnostic criteria for malignant NMLs were established using independent diagnostic indicators identified by binary logistic regression analysis. The diagnostic performance of Breast Imaging Reporting and Data System-US (BI-RADS-US), CEUS, and BI-RADS-US combined with CEUS was evaluated and compared.
resultsHistopathological results showed 63 and 56 benign and malignant NMLs. Enhancement degree (OR = 5.75,
conclusionsCEUS has a high specificity in malignant NML diagnosis based on the diagnostic criteria including enhancement degree, enhancement area, and radial or penetrating vessels, but with lower sensitivity than BI-RADS-US. The combination of CEUS and BI-RADS-US is an effective diagnostic tool with both high sensitivity and specificity for the diagnosis of malignant NMLs. ADVANCES IN KNOWLEDGE: In this study, we assessed the diagnostic value of CEUS for malignant NMLs and constructed a feasible diagnostic criterion. We further revealed that the combination of CEUS and BI-RADS-US has a high diagnostic value for malignant NMLs.
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