Evidence map›Paper›PMID 33560579›Full record

ArticleBrain and behavior2021

Cerebral areas affected by unilateral acupuncture on SP3 in healthy volunteers: An explorative resting-state fMRI study.

Feng Wang, Tiansong Yang, Xiaoling Li, Xiaohui Liu, Danna Cao, Delong Wang, Yan Yang, Chaoran Li, Yuanyuan Qu, Xu Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Feng WangFirst affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Tiansong YangFirst affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Xiaoling LiFirst affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Xiaohui LiuHeilongjiang University of Chinese Medicine, Harbin, China.
Danna CaoFirst affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Delong WangHeilongjiang University of Chinese Medicine, Harbin, China.
Yan YangHeilongjiang University of Chinese Medicine, Harbin, China.
Chaoran LiHeilongjiang University of Chinese Medicine, Harbin, China.
Yuanyuan QuHeilongjiang University of Chinese Medicine, Harbin, China.
Xu ZhaoFirst affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Zhongren SunHeilongjiang University of Chinese Medicine, Harbin, China.
Tetsuya AsakawaDepartment of Neurosurgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.ORCID 0000-0002-2300-3509
Heilongjiang University of Chinese Medicine · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNFujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to explore the cerebral areas with changes in regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) values induced by effective acupuncture on the Taibai (SP3) point.

methodsIn the study, 15 healthy right-handed volunteers (seven males and eight females, 20-35 years old) were enrolled. The average ages of the subjects were 28.0 ± 4.24 years for males and 27.4 ± 3.65 years for females. A 3.0T magnetic resonance imaging (MRI) system was used to perform resting-state functional MRI scan after sham and effective acupuncture on the SP3 point. The differences in cerebral ReHo and ALFF values between posteffective acupuncture and postsham acupuncture were compared using the SPM 12 software.

resultsReHo values of bilateral BA18, cuneus, and BA17, along with BA41, BA22, postcentral gyrus, and BA7 on the right side, were decreased by effective SP3 acupuncture. The ALFF values of bilateral BA 30 and left parahippocampal area were increased, whereas the values of bilateral BA18, BA19, cuneus, posterior cingulate gyrus, and BA7, along with the right superior occipital lobule, postcentral gyrus, and left precuneus, were decreased.

conclusionsThe most dominant cerebral areas affected by SP3 acupuncture were bilateral visual-related cortices (lingual gyrus, cuneus, and calcarine), along with the unilateral postcentral gyrus and superior parietal lobule. These findings may be potential explanations for the available clinical reports concerning the efficacy of SP3 acupuncture. Further clinical and experimental studies on SP3 acupuncture are required.

Indexed as

AcupunctureAcupuncture TherapyAcupuncture PointsAdultBrainFemaleHealthy VolunteersHumansMagnetic Resonance ImagingMaleYoung Adultacupunctureamplitude of low-frequency fluctuationregional homogeneityresting-state functional magnetic resonance imagingTaibai (SP3)

Identifiers

PMID33560579
PMCPMC8035461
OpenAlexW3128810557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.