Evidence map›Paper›PMID 33560522›Full record

ArticleJournal of clinical laboratory analysis2021

Liquid nitrogen for cryotherapy treatment for osteosarcoma of the middle femur: A case report.

Cheng Liu, Cuili Shu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cheng LiuDepartment of Orthopedics, Guangdong Clifford Hospital, Guangzhou, China.ORCID https://orcid.org/0000-0002-0275-176X
Cuili ShuDepartment of Orthopedics, Guangdong Clifford Hospital, Guangzhou, China.

Funding

General Program of National Natural Science Foundation of China 31671304
6 · The paper itself

Abstract

backgroundOsteosarcoma is the most common primary malignant bone tumor in children and adolescents. Cryotherapy liquid nitrogen has been used an adjuvant treatment for tumors for some decades. CASE PRESENTATION: A 23-year-old male patient was admitted to our hospital, mainly due to progressive pain in his left thigh, and confirmed osteosarcoma by local biopsy. A total length of 28 cm tumor bone was completely resected at the region of above and below lesion 3 cm under the guidance of MRI. After removed part of the tumor tissue, tumor bone was dealt with liquid nitrogen for 20 minutes. Finally, the bone was fixed with intramedullary needles for reconstruction. Three months after surgery, the X-ray examination showed poor bone growth at both distal sides of osteotomy and disuse degeneration of knee joint. The patient was performed an incision on the lateral side of the distal left thigh to secure the locking plate, and followed up every 3 months. Two years after operation, there was no sign of local recurrence.

conclusionLiquid nitrogen for cryotherapy may be a feasible local therapy for large lesion of osteosarcoma in middle femur.

Indexed as

Bone NeoplasmsCryotherapyFemurHumansMaleNitrogenOsteosarcomaOsteotomyTreatment OutcomeYoung AdultNitrogenbone tumorcryotherapy liquid nitrogenmiddle femurosteosarcomareconstruction

Identifiers

PMID33560522
PMCPMC7957967
OpenAlexW3126638391

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.