Evidence map›Paper›PMID 33560496›Full record

ArticleAdvances in therapy2021

A Japanese Study Assessing Glycemic Control with Use of IDegAsp Co-formulation in Patients with Type 2 Diabetes in Clinical Practice: The JAGUAR Study.

Shizuka Kaneko, João D da Rocha Fernandes, Yuiko Yamamoto, Jakob Langer, Mads Faurby

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Article
  6. Practical guide in using insulin degludec/insulin aspart: A multidisciplinary approach in Malaysia.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shizuka KanekoDivision of Diabetes/Endocrinology/Lifestyle-Related Disease, Takatsuki Red Cross Hospital, Takatsuki, Japan. ayamoesk3218@takatsuki.jrc.or.jp.ORCID http://orcid.org/0000-0001-6741-218X
João D da Rocha FernandesNovo Nordisk A/S, Vandtårnsvej, Søborg, Denmark.
Yuiko YamamotoNovo Nordisk Pharma Ltd, Tokyo, Japan.
Jakob LangerNovo Nordisk Pharma Ltd, Tokyo, Japan.
Mads FaurbyNovo Nordisk A/S, Vandtårnsvej, Søborg, Denmark.
Novo Nordisk (Denmark) · DKTakatsuki Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to evaluate the glycemic control and safety of insulin degludec/insulin aspart (IDegAsp) co-formulation in Japanese patients with type 2 diabetes (T2D) in a real-world clinical setting, including elderly patients (aged > 75 years).

methodsPatients (≥ 18 years) diagnosed with T2D, previously treated with insulin were included from the Japanese Medical Data Vision database. Baseline data were taken at the index date, defined as the first IDegAsp prescription claim. Change in glycated hemoglobin (HbA

resultsOverall, 10,798 patients were included, 3940 were aged > 75 years, and 913 had baseline HbA

conclusionSwitching from insulin to IDegAsp co-formulation was associated with significantly improved glycemic control and a reduction in hypoglycemia rate during 12 months of follow-up in Japanese patients with T2D, including those aged > 75 years.

Indexed as

Diabetes Mellitus, Type 2PantheraAgedBlood GlucoseGlycated HemoglobinGlycemic ControlHumansHypoglycemic AgentsInsulin AspartJapanBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulin AspartElderlyHypoglycemiaIDegAspInsulinJapanReal-worldType 2 diabetes

Identifiers

PMID33560496
PMCPMC7932946
OpenAlexW3127077340

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.