Evidence map›Paper›PMID 33560464›Full record

ReviewCurrent allergy and asthma reports2021

Asthma in Cystic Fibrosis: Definitions and Implications of This Overlap Syndrome.

Chad R Marion, Manuel Izquierdo, Holly C Hanes, Christopher Barrios

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Asthma and respiratory comorbidities.The Journal of allergy and clinical immunology · 2025
    Review
  4. Bronchodilator response assessment through impulse oscillometry system and spirometry in children and adolescents with cystic fibrosis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024
    Article
  5. The impact of CFTR modulator triple therapy on type 2 inflammatory response in patients with cystic fibrosis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chad R MarionDepartment of Internal Medicine, Section on Pulmonary and Critical Care Medicine, Wake Forest Baptist Hospital, Winston-Salem, NC, USA.
Manuel IzquierdoDepartment of Internal Medicine, Section on Pulmonary and Critical Care Medicine, Wake Forest Baptist Hospital, Winston-Salem, NC, USA.
Holly C HanesDepartment of Pediatrics, Section on Pulmonary Medicine, Wake Forest Baptist Hospital, Winston-Salem, NC, USA.
Christopher BarriosDepartment of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA. Christopher.barrios@health.slu.edu.ORCID 0000-0001-5522-5432
Atrium Health Wake Forest Baptist · USSaint Louis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCystic fibrosis (CF) is a multisystem, autosomal recessive disease that leads to progressive loss of lung function. Respiratory symptoms for both CF and asthma include cough, wheezing, and dyspnea. There is debate within the CF community on how to best define and distinguish CF-asthma overlap syndrome (CFAOS) from asthma-like features, though CFAOS is well-recognized. We aim to review the epidemiology, diagnosis, and treatment of asthma in CF and explore areas where further research is needed. RECENT

findingsThere has been considerable improvement in the understanding and treatment of asthma over the past two decades leading to novel therapies such as biologic agents that target the airway inflammation in asthmatics based on their asthma phenotype. These therapies are being studied in CFAOS and are promising treatments. This review provides a comprehensive overview of the definition, epidemiology, diagnosis, and current treatment of CFAOS.

Indexed as

AsthmaCystic FibrosisHumansInflammationRespiratory SystemSyndromeAsthmaCystic fibrosisCystic fibrosis-asthma overlap syndrome

Identifiers

PMID33560464
OpenAlexW3126609917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.