ArticlePediatric nephrology (Berlin, Germany)2021
Acute rejection and growth outcomes in paediatric kidney allograft recipients treated with a corticosteroid minimisation immunosuppressive protocol.
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Circadian blood pressure patterns in kidney transplant recipients assessed by ambulatory blood pressure monitoring.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Weight of evidence: reevaluating BMI criteria as a barrier for kidney transplantation in children.Pediatric nephrology (Berlin, Germany) · 2025Article
- Current status of glucocorticoid usage in solid organ transplantation.World journal of transplantation · 2021Review
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Authors and funding
2 authors at 2 institutions in 1 country.
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Abstract
backgroundCorticosteroid minimisation immunosuppressive protocols (CMP) for children are an approach to safely reduce unwanted medication side effects associated with long-term exposure following kidney transplantation. Here, we provide data regarding the incidence of acute rejection and growth over an extended follow-up in children receiving the CMP used in our centre.
methodsWe retrospectively analysed all children treated with a CMP who received a kidney transplant and had follow-up care in our centre between 2009 and 2019. Data were compared to 5 control groups from recent studies.
resultsNinety-nine kidney allograft recipients were included in the study (mean follow-up 4.4 years). There was no difference in the cumulative frequency of acute rejection in CMP-treated graft recipients compared to controls. Graft function at latest follow-up was significantly lower in graft recipients experiencing acute rejection compared to those without acute rejection (53.7 mL/min/1.73 m
conclusionsChildren treated with a CMP show greater height attainment, lower frequency of obesity, and reduced rates of hypertension, without an increased risk of acute rejection. Graphical abstract.
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