Evidence map›Paper›PMID 33560348›Full record

ArticleSystematic biology2022

Gene Tree Discord, Simplex Plots, and Statistical Tests under the Coalescent.

Elizabeth S Allman, Jonathan D Mitchell, John A Rhodes

Open access · greenAbstract read
In one paragraph

Article in Systematic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. NANUQAlgorithms for molecular biology : AMB · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Elizabeth S AllmanDepartment of Mathematics and Statistics, University of Alaska Fairbanks, Fairbanks, AK 99709, USA.
Jonathan D MitchellDepartment of Mathematics and Statistics, University of Alaska Fairbanks, Fairbanks, AK 99709, USA.
John A RhodesDepartment of Mathematics and Statistics, University of Alaska Fairbanks, Fairbanks, AK 99709, USA.
University of Alaska Fairbanks · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Mathematical and computational analysis for species tree inferenceR01GM117590 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI RHODES, JOHN · 2015 to 2018
$1.5M
NIGMS NIH HHS P20 GM103395NIGMS NIH HHS R01 GM117590NIH HHS 2P20 GM103395NIH HHS R01 GM117590
6 · The paper itself

Abstract

A simple graphical device, the simplex plot of quartet concordance factors, is introduced to aid in the exploration of a collection of gene trees on a common set of taxa. A single plot summarizes all gene tree discord and allows for visual comparison to the expected discord from the multispecies coalescent model (MSC) of incomplete lineage sorting on a species tree. A formal statistical procedure is described that can quantify the deviation from expectation for each subset of four taxa, suggesting when the data are not in accord with the MSC, and thus that either gene tree inference error is substantial or a more complex model such as that on a network may be required. If the collection of gene trees is in accord with the MSC, the plots reveal when substantial incomplete lineage sorting is present. Applications to both simulated and empirical multilocus data sets illustrate the insights provided. [Gene tree discordance; hypothesis test; multispecies coalescent model; quartet concordance factor; simplex plot; species tree].

Indexed as

Genetic SpeciationModels, GeneticComputer SimulationPhylogeny

Identifiers

PMID33560348
PMCPMC9203069
OpenAlexW3128747563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.