Evidence map›Paper›PMID 33560340›Full record

ArticleRheumatology (Oxford, England)2021

Estimating the population health burden of musculoskeletal conditions using primary care electronic health records.

Dahai Yu, George Peat, Kelvin P Jordan, James Bailey, Daniel Prieto-Alhambra, Danielle E Robinson, Victoria Y Strauss, Karen Walker-Bone, Alan Silman, Mamas Mamas and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Dahai YuPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.ORCID 0000-0002-8449-7725
George PeatPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Kelvin P JordanPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
James BaileyPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Daniel Prieto-AlhambraCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford.
Danielle E RobinsonCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford.
Victoria Y StraussCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford.
Karen Walker-BoneMRC Versus Arthritis Centre for Musculoskeletal Health and Work, University of Southampton, Southampton.
Alan SilmanCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford.
Mamas MamasKeele Cardiovascular Research Group, Centre for Prognosis Research, School of Medicine, Keele University, Keele.
Steven BlackburnPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Stephen DentPublic Contributor.ORCID 0000-0002-9393-6283
Kate DunnPrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Andrew JudgeCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford.
Joanne ProtheroePrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Ross WilkiePrimary Care Centre Versus Arthritis, School of Medicine, Keele University.
Arthritis UK · GBNuffield Orthopaedic Centre · GBKeele University · GB

Funding

Honorary Academic Consultant Contracts from Public Health EnglandMedical Research Council MC_PC_15015Medical Research Council MC_U147585823Medical Research Council MC_UU_12011/5National Institute for Health Research (NIHR) Oxford Biomedical Research CentreNIHR Applied Research Collaboration (West Midlands)NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of BristolNIHR Senior Research Fellowship SRF-2018-11-ST2-004PRELIMVersus Arthritis 21403
6 · The paper itself

Abstract

objectivesBetter indicators from affordable, sustainable data sources are needed to monitor population burden of musculoskeletal conditions. We propose five indicators of musculoskeletal health and assessed if routinely available primary care electronic health records (EHR) can estimate population levels in musculoskeletal consulters.

methodsWe collected validated patient-reported measures of pain experience, function and health status through a local survey of adults (≥35 years) presenting to English general practices over 12 months for low back pain, shoulder pain, osteoarthritis and other regional musculoskeletal disorders. Using EHR data we derived and validated models for estimating population levels of five self-reported indicators: prevalence of high impact chronic pain, overall musculoskeletal health (based on Musculoskeletal Health Questionnaire), quality of life (based on EuroQoL health utility measure), and prevalence of moderate-to-severe low back pain and moderate-to-severe shoulder pain. We applied models to a national EHR database (Clinical Practice Research Datalink) to obtain national estimates of each indicator for three successive years.

resultsThe optimal models included recorded demographics, deprivation, consultation frequency, analgesic and antidepressant prescriptions, and multimorbidity. Applying models to national EHR, we estimated that 31.9% of adults (≥35 years) presenting with non-inflammatory musculoskeletal disorders in England in 2016/17 experienced high impact chronic pain. Estimated population health levels were worse in women, older aged and those in the most deprived neighbourhoods, and changed little over 3 years.

conclusionNational and subnational estimates for a range of subjective indicators of non-inflammatory musculoskeletal health conditions can be obtained using information from routine electronic health records.

Indexed as

Cost of IllnessAdultAgedAged, 80 and overAge FactorsElectronic Health RecordsEnglandFemaleHumansMaleMiddle AgedModels, StatisticalMusculoskeletal DiseasesPrimary Health CareSex FactorsSurveys and Questionnairesback painelectronic health recordshealth services researchmusculoskeletalpainprimary carequality of lifeshoulder painsurveillance

Identifiers

PMID33560340
PMCPMC8487274
OpenAlexW3126190064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.