Evidence map›Paper›PMID 33560298›Full record

ArticleRheumatology (Oxford, England)2021

Association of particulate matter with autoimmune rheumatic diseases among adults in South Korea.

Jun Seok Park, Seulggie Choi, Kyuwoong Kim, Jooyoung Chang, Sung Min Kim, Seong Rae Kim, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Eun Young Lee and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  8. The Relationship between Climate Change and Rheumatic Disease: A Review.International archives of allergy and immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jun Seok ParkCollege of Medicine, Seoul National University Hospital.ORCID 0000-0002-1301-7165
Seulggie ChoiDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul.
Kyuwoong KimDivision of Cancer Control and Policy, National Cancer Control Institute, National Cancer Center, Goyang.ORCID 0000-0002-2824-8441
Jooyoung ChangDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul.
Sung Min KimDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul.
Seong Rae KimCollege of Medicine, Seoul National University Hospital.ORCID 0000-0003-3556-3009
Gyeongsil LeeDepartment of Family Medicine, Seoul National University Hospital.
Joung Sik SonDepartment of Family Medicine, Seoul National University Hospital.ORCID 0000-0003-2460-3378
Kyae Hyung KimDepartment of Family Medicine, Seoul National University Hospital.
Eun Young LeeDivision of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Sang Min ParkDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul.ORCID 0000-0002-7498-4829
Seoul National University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe primary objective of this study was to investigate adverse effects of ambient particulate matter of various sizes on the incidence of the prevalent autoimmune rheumatic diseases (AIRDs): RA, AS and SLE.

methodsWe investigated 230 034 participants in three metropolitan cities of South Korea from the National Health Insurance Service-National Sample Cohort (NHIS-NSC). Starting from January 2010, subjects were followed up until the first event of prevalent AIRDs, death, or December 2013. The 2008-2009 respective averages of particulate matter2.5 (<2.5 μm) and particulate mattercoarse (2.5 μm to 10 μm) were linked with participants' administrative district codes. Adjusted hazard ratios (aHRs) and 95% CIs were estimated using Cox regression analysis in one- and two-pollutant models.

resultsAdjusted for age, sex, region, and household income, in the two-pollutant model, RA incidence was positively associated with the 10 μg/m³ increment of particulate matter2.5 (aHR = 1.74, 95% CI: 1.06, 2.86), but not with particulate mattercoarse (aHR = 1.27, 95% CI: 0.87, 1.85). In the one-pollutant model, the elevated incidence rate of RA was slightly attenuated (particulate matter2.5 aHR = 1.61, 95% CI: 0.99, 2.61; particulate mattercoarse aHR = 1.13, 95% CI: 0.80, 1.61), with marginal statistical significance for particulate matter2.5. The RA incidence was also higher in the 4th quartile group of particulate matter2.5 compared with the first quartile group (aHR = 1.83, 95% CI: 1.07, 3.11). Adverse effects from particulate matter were not found for AS or SLE in either the one- or two-pollutant models.

conclusionThe important components of particulate matter10 associated with RA incidence were the fine fractions (particulate matter2.5); no positive association was found between particulate matter and AS or SLE.

Indexed as

AdultAgedAutoimmune DiseasesFemaleHumansIncidenceMaleMiddle AgedParticulate MatterRepublic of KoreaRetrospective StudiesRheumatic DiseasesYoung AdultParticulate Matterankylosing spondylitisepidemiologyparticulate matterrheumatoid arthritissystemic lupus erythematosus

Identifiers

PMID33560298
PMCPMC8566218
OpenAlexW3127403402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.