ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021
The prevalence and impact of pre-existing sleep disorder diagnoses and objective sleep parameters in patients hospitalized for COVID-19.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Significant association of obstructive sleep apnoea with increased risk for fatal COVID-19: A quantitative meta-analysis based on adjusted effect estimates.Sleep medicine reviews · 2022Pooled it
- Obstructive sleep apnea, positive airway pressure therapy, and COVID-19 outcomes.Sleep & breathing = Schlaf & Atmung · 2026Article
- Optimizing Sleep Disorder Management in Hospitalized Patients: Practical Approach for Healthcare Providers.Brain and behavior · 2025Review
- Associations between obstructive sleep apnea and COVID-19 infection and hospitalization among US adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- COVID-19 and Sleep Disturbances: A Literature Review of Clinical Evidence.Medicina (Kaunas, Lithuania) · 2023Review
- Review
- Inventory study of an early pandemic COVID-19 cohort in South-Eastern Sweden, focusing on neurological manifestations.PloS one · 2023Observational
- Sleep and critical illness: a review.Frontiers in medicine · 2023Review
- Characteristics of Sleep Disturbance in Patients with Long COVID: A Retrospective Observational Study in Japan.Journal of clinical medicine · 2022Article
- The Relationship between the Severity of the COVID-19 Disease, Temperament and Psychological Factors.Iranian journal of psychiatry · 2022Article
- Negative association between fatigue and signs of sleep apnoea in patients after COVID-19.ERJ open research · 2022Article
- The CSHQ-DE Questionnaire Uncovers Relevant Sleep Disorders in Children and Adolescents with Long COVID.Children (Basel, Switzerland) · 2022Article
- [Cognitive disorders and sleep disturbances in long COVID].Der Nervenarzt · 2022Review
- Impact of home CPAP-treated obstructive sleep apnea on COVID-19 outcomes in hospitalized patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Review
- Is sleep disordered breathing a risk factor for COVID-19 orERJ open research · 2022Article
- Sleep disorders and COVID-19.Sleep medicine · 2022Article
- Insomnia and nightmare profiles during the COVID-19 pandemic in Portugal: characterization and associated factors.Sleep medicine · 2022Article
- Assessment of Insomnia and Associated Factors Among Patients Who Have Recovered from COVID-19 in Vietnam.Patient preference and adherence · 2022Article
- Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: A systematic review, meta-analysis and call for action.EClinicalMedicine · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectivesObstructive sleep apnea and other sleep disorders overlap with comorbidities associated with poor outcomes related to severe acute respiratory syndrome coronavirus 2 infection. However, the prevalence of obstructive sleep apnea among patients hospitalized for COVID-19 and relationship to outcomes is poorly characterized, and the relevance of other sleep disorders remains unknown. The objective of this study was to identify the prevalence of pre-existing sleep disorders and association with outcomes related to severe COVID-19 illness.
methodsPatients with severe acute respiratory syndrome coronavirus 2 infection admitted to the University of Michigan Hospital System were included. Electronic medical records were queried for sleep disorders diagnostic codes. Data were extracted from polysomnography and home sleep testing in a subgroup with previous diagnostic testing at our center. Logistic regression was used to examine the association of sleep disorders with mechanical ventilation requirement, treatment with vasopressors, and death and Cox proportional hazards regression for time to discharge.
resultsAmong n = 572 adult patients hospitalized for COVID-19, 113 (19.8%) patients had obstructive sleep apnea, 4 patients had central sleep apnea (0.7%), 5 had hypoventilation (0.9%), 63 had insomnia (11.0%), and 22 had restless legs syndrome or periodic limb movements disorder (3.9%). After adjusting for age, sex, body mass index, and race, no significant relationship was apparent between sleep disorders diagnoses or indices of sleep-disordered breathing severity and outcomes.
conclusionsThis is the first study to determine the prevalence of obstructive sleep apnea and other sleep disorders in a well-characterized cohort of patients hospitalized for COVID-19. Once hospitalized, a significant contribution of sleep disorders to outcomes was not identified. Therefore, future evaluations should focus on earlier outcomes, such as infection or clinical manifestations after exposure to severe acute respiratory syndrome coronavirus 2.
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