SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021
Obstructive sleep apnea in patients with head and neck cancer: a systematic review.
Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Obstructive Sleep Apnea Following Head and Neck Chemoradiation: A Scoping Review With Exploratory Meta-Analysis.Head & neck · 2026Pooled it
- Prevalence and assessment of sleep-disordered breathing in head and neck cancer patients: a systematic review.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Proposal for Managing Cancer-Related Insomnia: A Systematic Literature Review of Associated Factors and a Narrative Review of Treatment.Cancer medicine · 2024Pooled it
- Characterizing sleep-related complaints in head and neck cancer survivors with tumors of airway relevance following radiotherapy.Clinical and translational radiation oncology · 2026Article
- Cancer History and Subjective Sleepiness in Obstructive Sleep Apnea: A Real-World Observational Study.Journal of clinical medicine · 2026Article
- Prevalence and Correlates of Sleep Difficulties in a Large Multicenter Outpatient Oncology Population as Identified through Practice-Based Screening.Cancer research communications · 2026Article
- Article
- Prevalence of obstructive sleep apnea after treatment for advanced T-stage head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Comorbidities and Laryngeal Cancer in Patients with Obstructive Sleep Apnea: A Review.Medicina (Kaunas, Lithuania) · 2023Review
- Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea-A Narrative Review.Life (Basel, Switzerland) · 2023Review
- Screening for obstructive sleep apnea in patients with cancer - a machine learning approach.Sleep advances : a journal of the Sleep Research Society · 2023Article
- Risk of obstructive sleep apnea after treatment of head and neck squamous cell carcinoma: a cross-sectional study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Orofacial Pain and Snoring/Obstructive Sleep Apnea in Individuals with Head and Neck Cancer: A Critical Review.Journal of oral & facial pain and headache · 2022Review
- Obstructive Sleep Apnea in Head and Neck Cancer Survivors: A Systematic Review and Meta-Analysis.OTO openReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
STUDY
objectivesHead and neck cancers (HNCs) may modify the upper airway anatomy and thereby increase the risk for obstructive sleep apnea (OSA). If untreated, OSA is associated with adverse outcomes. Identification of risk factors for OSA in patients with HNC is essential to promote proper evaluation, treatment, and improvement of sleep-related outcomes. In this review, we assessed associations between tumor stage, cancer treatment, and OSA in the population with HNC.
methodsA systematic search of PubMed, EMBASE (Embase.com), Cochrane Library (Cochranelibrary.com), Scopus, and Web of Science was conducted to identify articles related to OSA in patients with HNC. A total of 215 articles were identified, of which 14 were included in the qualitative synthesis. These studies included 387 participants.
resultsThe most common cancer type, tumor location, and cancer therapy were squamous cell carcinoma, oropharynx, and surgery, respectively. Three of six articles reported an association between surgical treatment and OSA. Conversely, associations between tumor stage, radiotherapy, and OSA were found in only a minority of studies (15%). The prevalence of OSA was between 57% and 76% pre-cancer therapy and 12% and 96% afterward.
conclusionsThis review suggests a potential association between HNC surgery and OSA. An association between tumor stage, radiotherapy to the head and neck, and OSA is inconclusive. Further research is needed to examine the relationship between HNC and OSA.
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