Evidence map›Paper›PMID 33560106›Full record

ArticleBiochemistry2021

Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin.

Donella M Beckwith, Forrest G FitzGerald, Maria C Rodriguez Benavente, Elizabeth R Mercer, Anna-Kristin Ludwig, Malwina Michalak, Herbert Kaltner, Jürgen Kopitz, Hans-Joachim Gabius, Maré Cudic

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. What is the Sugar Code?Chembiochem : a European journal of chemical biology · 2022
    Review
  8. Mucin-TypeFrontiers in chemistry · 2022
    Article
  9. TyrosineACS chemical neuroscience · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Donella M BeckwithDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, Florida 33431, United States.
Forrest G FitzGeraldDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, Florida 33431, United States.
Maria C Rodriguez BenaventeDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, Florida 33431, United States.
Elizabeth R MercerDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, Florida 33431, United States.
Anna-Kristin LudwigLudwig-Maximilians-University Munich, Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Veterinärstrasse 13, 80539 Munich, Germany.
Malwina MichalakDepartment of Applied Tumor Biology, Institute of Pathology, Medical School of the Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
Herbert KaltnerLudwig-Maximilians-University Munich, Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Veterinärstrasse 13, 80539 Munich, Germany.
Jürgen KopitzDepartment of Applied Tumor Biology, Institute of Pathology, Medical School of the Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
Hans-Joachim GabiusLudwig-Maximilians-University Munich, Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Veterinärstrasse 13, 80539 Munich, Germany.ORCID 0000-0003-3467-3900
Maré CudicDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, Florida 33431, United States.ORCID 0000-0002-7657-0400
Florida Atlantic University · USLudwig-Maximilians-Universität München · DEHeidelberg University · DE

Funding

Mechanistic insight into tumor-associated MUC1 glycopeptides binding to macrophage galactose-type lectinR15CA242351 · NCI · FLORIDA ATLANTIC UNIVERSITY · PI CUDIC, MARE · 2019 to 2024
$878k
NCI NIH HHS R15 CA242351
6 · The paper itself

Abstract

Human macrophage galactose-type lectin (hMGL, HML, CD301, CLEC10A), a C-type lectin expressed by dendritic cells and macrophages, is a receptor for

Indexed as

Amino Acid SequenceAntigens, Tumor-Associated, CarbohydrateCalorimetryEpitopesGalactoseGlycopeptidesGlycosylationHumansLectins, C-TypeMacrophagesMucin-1Protein BindingAntigens, Tumor-Associated, CarbohydrateEpitopesGalactoseGlycopeptidesLectins, C-TypeMGL lectin, humanMUC1 protein, humanMucin-1sialosyl-Tn antigenTn antigen

Identifiers

PMID33560106
PMCPMC8269692
OpenAlexW3128188841

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.